Data from SDS-PAGE analysis of Anti-Adiponectin antibody (Clone ADPN/1370). Reducing lane (R) shows heavy and light chain fragments. NR lane shows intact antibody with expected MW of approximately 150 kDa. The data are consistent with a high purity, intact mAb.Formalin-fixed, paraffin-embedded human Kidney stained with Adiponectin Monoclonal Antibody (ADPN/137).

Anti-Adiponectin Antibody Clone ADPN/1370

$ 228.00$ 518.00
Please Select Product Options Below To View The Catalog Number.

SKU: 9370-MSM3
Species: Human
Tested Applications: Immunohistochemistry (IHC)
Available Conjugates: Unconjugated
Isotype: Mouse IgG2b
Mass Spec Validated?: Not MS Validated

Product NumberDescriptionPrice
9370-MSM3-P0 Size: 20 ug, Tag: Unconjugated $ 199.00
9370-MSM3-P1 Size: 100 ug, Tag: Unconjugated $ 429.00
9370-MSM3-P2 Size: 200 ug, Tag: Unconjugated $ 459.00
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In Stock.
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SKU: 9370-MSM3-P0
Adiponectin General Information
Alternate Names
Adiponectin, AdipoQ
Molecular Weight
26-30kDa
Chromosomal Location
3q27
Curated Database and Bioinformatic Data
Gene SymbolADIPOQ
Entrez Gene ID9370
Ensemble Gene IDENSG00000181092
RefSeq Protein Accession(s)NP_004788, NP_001171271
RefSeq mRNA Accession(s)NM_004797, NM_001177800
RefSeq Genomic Accession(s)NC_018914, NC_000003, NG_021140
UniProt ID(s)A8K660, Q15848, B2R773
UniGene ID(s)A8K660, Q15848, B2R773
HGNC ID(s)13633
Cosmic ID(s)ADIPOQ
KEGG Gene ID(s)hsa:9370
PharmGKB ID(s)PA134933118
General Description of Adiponectin.
This MAb reacts with adiponectin, an adipocytokine. Adipocytokines are hormones produced in adipose tissue. Adiponectin is abundantly present in plasma and has insulin like effect on glucose levels in the blood. Plasma adiponectin levels are low in insulin resistant patients who are obese, have diabetes mellitus type 2 or HIV-lipodystrophy. In women adiponectin levels tend to be higher than in men, which may be due to androgens suppressing adiponectin levels. Furthermore adiponectin and leptin are both indicated in regulating body weight through direct action on the hypothalamus, influencing appetite. Obese people have low adiponectin levels while levels in anorexia patients are high. Adiponectin acts as ligand for various receptors, two of which have been identified, one probably involved in carbohydrate assimilation, the other in tuning the rate of metabolism.

Human Anti-Adiponectin Antibody Product Attributes

Species: Human
Tested Applications: Immunohistochemistry (IHC).
Clonality: Monoclonal
Anti-Adiponectin Antibody Clone: ADPN/1370
Clone ADPN/1370 Host and Isotype: Mouse IgG2b
Anti-Human Adiponectin Positive Control Sample: HeLa cells or Kidney
Cellular Localization of Antibody Cytoplasmic ;Cell Surface
Buffer and Stabilizer: 10mM PBS with 0.05% BSA and 0.05% Azide
Antibody Concentration: 200 ug/ml
Antibody Purification Method:Protein A/G Purified
Immunogen: Recombinant human Adiponectin protein fragment
Storage Conditions: Store at 2 to 8° C (refrigerate). Stable for 24 months when properly stored.

Adiponectin Previously Observed Antibody Staining Patterns

Observed Antibody Staining Data By Tissue Disease Status:

Tissues from cancer patients, for instance, have their own distinct pattern of Adiponectin expression as measured by anti-Adiponectin antibody immunohistochemical staining. The average level of expression by tumor is summarized in the table below. The variability row represents patient to patient variability in IHC staining.

Sample Type breast cancer carcinoid cervical cancer colorectal cancer endometrial cancer glioma head and neck cancer liver cancer lung cancer lymphoma melanoma ovarian cancer pancreatic cancer prostate cancer renal cancer skin cancer stomach cancer testicular cancer thyroid cancer urothelial cancer
Signal Intensity - - - - - - - - - - - - - - - + - - - -
ADIPOQ Variability + ++ + + + + ++ ++ + + + + + + + ++ + + ++ +

Limitations and Warranty

enQuire Bio's Adiponectin Anti-Human Monoclonal is available for Research Use Only. This antibody is guaranteed to work for a period of two years when properly stored.

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Anti-Adiponectin Antibody Clone ADPN/1370

https://enquirebio.com/wp-content/uploads/2019/01/Anti-Adiponectin Specificity Assay (Array)-300x120.jpghttps://enquirebio.com/wp-content/uploads/2019/01/Adiponectin IHC human Kidney (ADPN 1370)-300x225.jpghttps://enquirebio.com/wp-content/uploads/2019/01/Anti-Adiponectin(ADPN 1370) Gel-231x300.jpghttps://enquirebio.com/wp-content/uploads/2019/01/Adiponectin WB human kidney lysates (clone ADPN 1370)-142x300.jpghttps://enquirebio.com/wp-content/uploads/2017/10/enQuire-Bio-9370-MSM3-P0-anti-Adiponectin-antibody-300x225.jpeg