Immunohistochemical staining of Albumin  of human FFPE tissue followed by incubation with HRP labeled secondary and development with DAB substrate.

Albumin [Polyclonal] Antibody (cGMP).

$ 128.00$ 188.00
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SKU: QIVD73
Species: Human
Tested Applications: IHC [IVD]
Available Conjugates:
Isotype: Rabbit Undetermined

Product NumberDescriptionPrice
QIVD73-0.1ml Size: 0.1 ml, Format: Concentrate $ 128.00
QIVD73-0.5ml Size: 0.5 ml, Format: Concentrate $ 138.00
QIVD73-1ml Size: 1 ml, Format: Concentrate $ 188.00
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Datasheets and Documentation
Product Datasheet
Certificate of Analysis and Tags (Coming Soon)
Lot Number:

Expiration Date:

Concentration (Write Lyophilized if Lyophilized):

Reconsitution Instructions (Leave Blank if Liquid):

Manufacture Date:

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Bioactivity (test results eg. IU/ml):


SKU: QIVD73-0.1ml
Albumin General Information
Alternate Names
Molecular Weight
69.4 kDa
Chromosomal Location
q13.3 [chr: 4] [chr_start: 73397114] [chr_end: 73421482] [strand: 1]
Curated Database and Bioinformatic Data
Gene SymbolALB
Entrez Gene ID213
RefSeq Protein Accession(s)NP_000468
RefSeq mRNA Accession(s)NM_000477;
RefSeq Genomic Accession(s)NG_009291; NC_000004
UniProt ID(s)P02768
PharmGKB ID(s)PA24690
KEGG Gene ID(s)hsa:213
Associated Diseases (KEGG IDs)Hyperthyroxinemia, familial dysalbuminemic (FDAH) [MIM:615999]: A disorder characterized by abnormally elevated levels of total serum thyroxine (T4) in euthyroid patients. It is due to abnormal serum albumin that binds T4 with enhanced affinity. {ECO:0000269|PubMed:7852505, ECO:0000269|PubMed:8048949, ECO:0000269|PubMed:9329347, ECO:0000269|PubMed:9589637}. The disease is caused by mutations affecting the gene represented in this entry.; Analbuminemia (ANALBA) [MIM:616000]: A rare autosomal recessive disorder manifested by the presence of a very low amount of circulating serum albumin. Affected individuals manifest mild edema, hypotension, fatigue, and, occasionally, lower body lipodystrophy (mainly in adult females). The most common biochemical finding is hyperlipidemia, with a significant increase in the total and LDL cholesterol concentrations, but normal concentrations of HDL cholesterol and triglycerides. {ECO:0000269|PubMed:8134387}. The disease is caused by mutations affecting the gene represented in this entry.
General Description of Albumin .
This antibody reacts with human albumin. This antibody is essentially free of other rabbit serum proteins. Specificity is determined by Ouchterlony double diffusion (ODD) and immunoelectrophoresis (IEP) versus human serum and human albumin.

Antibody (Suitable for clinical applications)

Sample Type: FFPE Patient Samples.
Tested Applications: IHC. Approved for In Vitro Diagnostic Procedures on FFPE tissues. For tissue collection recommendations, please see datasheet sent with product.
Application Notes
Specification Recommendation
Recommended Dilution (Conc) 1:50-1:100
Pretreatment No Pretreatment Required
Incubation Parameters 30 min at Room Temperature

Prior to use, inspect vial for the presence of any precipitate or other unusual physical properties. These can indicate that the antibody has degraded and is no longer suitable for patient samples. Please run positive and negative controls simultaneously with all patient samples to account and control for errors in laboratory procedure. Use of methods or materials not recommended by enQuire Bio including change to dilution range and detection system should be routinely validated by the user.

Clonality: Polyclonal
Anti-Albumin Antibody Clone: Polyclonal
Host and Isotype: Rabbit Undetermined
Recommended Positive Control Sample: Liver
Cellular Localization of Antibody Polyclonal Staining: Cytoplasmic
Buffer and Stabilizer: PBS with 1% BSA and 0.05% NaN3
Antibody Concentration: Lot specific. Plese contact tech support for data.
Immunogen: Purified human albumin.
Storage Conditions: This antibody should be stored refrigerated (2-8°C). This product should not be used past the expiration date printed on the vial.

Albumin Information for Pathologists

Summary:

Most common serum protein. 65K protein produced by ALB gene on #4, by liver (Wikipedia). 50% of total plasma protein content; usual serum concentration of 40 g/L. Binds to water, bilirubin, calcium, fatty acids, hormones (acts as carrier protein), potassium, sodium, and various drugs. Main function of serum albumin is to regulate blood colloidal osmotic pressure.

Notable Clinical Features:

Laboratory:. For serum albumin measure, most instrument systems do NOT have satisfactory total-error performance (Arch Pathol Lab Med 2013;137:912). Serum albumin may be a low cost diagnostic marker for tuberculosis in HIV+ patients eligible for antiretroviral therapy (Bioimpacts 2013;3:123). In type 2 diabetes patients with stable angina and chronic total coronary occlusion, increased serum glycated albumin levels are associated with impaired coronary collateral growth (Cardiovasc Diabetol 2013;12:165). Deficiency causes familial dysalbuminemic hyperthyroxinemia (MIM:103600).

Limitations and Warranty

This antibody is manufactured in accordance with clinical good manufacturing practices in an ISO13485:2016 certified production facility. It is intended for multiple uses including in vitro diagnostic use and research use only applications. Please see vial label for expiration date. We strive to always deliver antibodies with a shelf life of at least two years.

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Albumin [Polyclonal] Antibody (cGMP).