Antibody (Suitable for clinical applications)
Sample Type: FFPE Patient Samples.
Tested Applications: IHC. Approved for In Vitro Diagnostic Procedures on FFPE tissues. For tissue collection recommendations, please see datasheet sent with product.
|Recommended Dilution (Conc)||1:50-1:150|
|Pretreatment||No Pretreatment Required|
|Incubation Parameters||30 min at RoomTemperature|
Prior to use, inspect vial for the presence of any precipitate or other unusual physical properties. These can indicate that the antibody has degraded and is no longer suitable for patient samples. Please run positive and negative controls simultaneously with all patient samples to account and control for errors in laboratory procedure. Use of methods or materials not recommended by enQuire Bio including change to dilution range and detection system should be routinely validated by the user.
Anti-alpha-1-Fetoprotein Antibody Clone: Polyclonal
Host and Isotype: Rabbit Undetermined
Recommended Positive Control Sample: Fetal liver
Cellular Localization of Antibody Polyclonal Staining: Cytoplasmic
Buffer and Stabilizer: PBS with 1% BSA and 0.05% NaN3
Antibody Concentration: Lot specific. Plese contact tech support for data.
Immunogen: alpha-1-fetoprotein isolated from human cord serum.
Storage Conditions: This antibody should be stored refrigerated (2-8°C). This product should not be used past the expiration date printed on the vial.
alpha-1-Fetoprotein Information for Pathologists
Summary:Major plasma protein of early fetus; present in fetal gut, liver and yolk sac (Wikipedia). Serum levels may be elevated if severe hypothyroidism (J Pediatr Endocrinol Metab 2012;25:761). Uses by pathologists Serum marker:. Elevated in maternal serum or amniotic fluid ( > 2.5 multiples of median at a specified gestational age) if fetal developmental anomalies.
Common Uses By Pathologists:Serum marker:. Elevated in maternal serum or amniotic fluid ( > 2.5 multiples of median at a specified gestational age) if fetal developmental anomalies. Serum tumor marker elevated in patients with hepatoblastoma (eMedicine), hepatocellular carcinoma, hepatoid adenocarcinoma, testicular cancer (other than pure seminoma) and yolk sac tumor, but not in intrahepatic cholangiocarcinoma (Am Surg 2010;76:1210). Preoperative levels are prognostic for hepatocellular carcinoma (World J Surg Oncol 2013;11:212). Immunostain:.
Limitations and Warranty
This antibody is manufactured in accordance with clinical good manufacturing practices in an ISO13485:2016 certified production facility. It is intended for multiple uses including in vitro diagnostic use and research use only applications. Please see vial label for expiration date. We strive to always deliver antibodies with a shelf life of at least two years.
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