Anti-CD314 Antibody [CX5]

$ 119.00
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Species: Mouse
Tested Applications: Flow Cytometry
Available Conjugates: Unconjugated
Isotype: Rat IgG1 kappa
Mass Spec Validated?: Not MS Validated

Product NumberDescriptionPrice
QAB100-100ug Size: 100 ug, Tag: Unconjugated
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In Stock.
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Datasheets and Documentation
Product Datasheet
Certificate of Analysis and Tags (Coming Soon)
Lot Number:

Expiration Date:

Concentration (Write Lyophilized if Lyophilized):

Reconsitution Instructions (Leave Blank if Liquid):

Manufacture Date:


Bioactivity (test results eg. IU/ml):

SKU: QAB100-100ug
Anti-CD314 General Information
Alternate Names
NKG2D, CD314, KLR, NKG2-D, NKG2D, D12S2489E, CD314
Curated Database and Bioinformatic Data
Entrez Gene ID27007
Ensemble Gene IDENSMUSG00000030149
RefSeq Protein Accession(s)NP_001272947, NP_149069, NP_001076791, XP_011239671
RefSeq mRNA Accession(s)NM_001286018, NM_033078, XM_011241369, NM_001083322
RefSeq Genomic Accession(s)NC_000072
UniProt ID(s)Q4FJM0, Q3TCW7, O54709
UniGene ID(s)Q4FJM0, Q3TCW7, O54709
Cosmic ID(s)Klrk1
KEGG Gene ID(s)mmu:27007
General Description of Anti-CD314.
The CX5 antibody is specific for mouse NKG2D (CD314, KLRK1), a lectin-like type II transmembrane receptor protein. NKG2D functions as an activating receptor on NK cells and a co-stimulatory receptor on cytotoxic T cells, in both cases associating with the DAP10 adaptor protein. It is not expressed on resting T cells or unstimulated macrophages. NKG2D binds to its ligands, often expressed on atypical cells, including MULT1, H60 and five RAE1 variants. The CX5 antibody is reported to block binding of NKG2D to its ligands. Please choose the appropriate format for each application.

Mouse Anti-Anti-CD314 Antibody Product Attributes

Species: Mouse
Tested Applications: Flow Cytometry.
Application Notes: See Product Datasheet for Recommended Dilution Range. Requires Experimental Optimization
Clonality: Monoclonal Antibody
Anti-Anti-CD314 Antibody Clone: CX5
Clone CX5 Host and Isotype: Rat IgG1 kappa
Buffer and Stabilizer: 10 mM NaH2PO4, 150 mM NaCl, 0.09% NaN3, pH 7.2
Antibody Concentration: 0.5 mg/mL
Storage Conditions: 2-8C protected from light. Stable for 12 Months. Do Not Freeze.

Anti-CD314 Previously Observed Antibody Staining Patterns

Observed Subcellular, Organelle Specific Staining Data:

Anti-KLRK1 antibody staining is expected to be primarily localized to the plasma membrane.

Selected References

Cerwenka A, Bakker AB, McClanahan T, Wagner J, Wu J, Phillips JH and Lanier LL. 2000. Immunity. 12(6): 721-727. Carayannopoulos LN, Naidenko OV, Fremont DH and Yokoyama WM. 2002. J Immunol. 169(8): 4079-4083.Hamerman JA, Ogasawara K and Lanier LL. 2004. J Immunol. 172(4): 2001-2005. (Flow cytometry)Ogawawara K, Mamerman JA, Hsin H, Chikuma S, Bour-Jordan H, Chen T, Pertel T, Carnaud C, Bluestone JA and Lanier LL. 2003. Immunity. 18: 41-51. (in vivo blocking)Andre MC, Siqurdardottir D, Kuttruff S, Pommerl B, Handgretinger R, Rammensee HG and Steinle A. 2012. Int J Cancer. 131(7): 1601-1610. (Flow cytometry)

Limitations and Warranty

enQuire Bio's Mouse Anti-CD314 Monoclonal is available for Research Use Only. This antibody is guaranteed to work for a period of two years when properly stored.

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Anti-CD314 Antibody [CX5]