Human Anti-ASRGL1 Antibody Product Attributes
Species: Human
Tested Applications: Immunohistochemistry (IHC).
Clonality: Monoclonal
Anti-ASRGL1 Antibody Clone: CRASH/1289
Clone CRASH/1289 Host and Isotype: Mouse IgG1
Anti-Human ASRGL1 Positive Control Sample: HeLa cells. Fallopian Tube, Endometrium, Uterus or Cervix.
Cellular Localization of Antibody Cytoplasmic and Nuclear
Buffer and Stabilizer: 10mM PBS with 0.05% BSA and 0.05% Azide
Antibody Concentration: 200 ug/ml
Antibody Purification Method:Protein A/G Purified
Immunogen: Recombinant human full-length ASRGL1
Storage Conditions: Store at 2 to 8° C (refrigerate). Stable for 24 months when properly stored.
ASRGL1 Previously Observed Antibody Staining Patterns
Observed Subcellular, Organelle Specific Staining Data:
Anti-ASRGL1 antibody staining is expected to be primarily localized to the microtubules and nucleoplasm.Observed Antibody Staining Data By Tissue Type:
Variations in ASRGL1 antibody staining intensity in immunohistochemistry on tissue sections are present across different anatomical locations. An intense signal was observed in cells in the seminiferous ducts in testis, glandular cells in the cervix and uterine, endometrium, epididymis and fallopian tube. More moderate antibody staining intensity was present in cells in the seminiferous ducts in testis, glandular cells in the cervix and uterine, endometrium, epididymis and fallopian tube. Low, but measureable presence of ASRGL1 could be seen in cells in the granular layer in cerebellum, cells in the tubules in kidney, glandular cells in the appendix, colon, duodenum, gallbladder, prostate and seminal vesicle, glial cells in the cerebral cortex, Leydig cells in the testis, neuronal cells in the caudate nucleus and cerebral cortex, neuropil in cerebral cortex, respiratory epithelial cells in the bronchus and nasopharynx, smooth muscle cells in the smooth muscle and urothelial cells in the urinary bladder. We were unable to detect ASRGL1 in other tissues. Disease states, inflammation, and other physiological changes can have a substantial impact on antibody staining patterns. These measurements were all taken in tissues deemed normal or from patients without known disease.Observed Antibody Staining Data By Tissue Disease Status:
Tissues from cancer patients, for instance, have their own distinct pattern of ASRGL1 expression as measured by anti-ASRGL1 antibody immunohistochemical staining. The average level of expression by tumor is summarized in the table below. The variability row represents patient to patient variability in IHC staining.| Sample Type | breast cancer | carcinoid | cervical cancer | colorectal cancer | endometrial cancer | glioma | head and neck cancer | liver cancer | lung cancer | lymphoma | melanoma | ovarian cancer | pancreatic cancer | prostate cancer | renal cancer | skin cancer | stomach cancer | testicular cancer | thyroid cancer | urothelial cancer |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Signal Intensity | + | - | - | - | +++ | + | - | - | - | - | - | ++ | - | + | ++ | - | - | + | - | - |
| ASRGL1 Variability | +++ | ++ | ++ | ++ | ++ | ++ | ++ | + | + | + | + | ++ | ++ | ++ | ++ | + | ++ | ++ | ++ | + |
Limitations and Warranty
enQuire Bio's ASRGL1 Anti-Human Monoclonal is available for Research Use Only. This antibody is guaranteed to work for a period of two years when properly stored.
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