Formalin-fixed, paraffin-embedded human Colon Carcinoma stained with Blood Group Antigen A Monoclonal Antibody (3-3A)

Anti-Blood Group Antigen A Antibody Clone 3-3A

Name: Anti-Blood Group Antigen A Antibody Clone 3-3A
Brand: enQuire Bio
Price: 429 USD
Availability: InStock

$ 429.00

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SKU: 28-MSM9
Species: Human
Tested Applications: Immunofluorescence, Immunohistochemistry (IHC)
Available Conjugates: Unconjugated
Isotype: Mouse IgG1 kappa
Mass Spec Validated?: Not MS Validated

Product Number	Description	Price
28-MSM9-P1	Size: 100 ug, Tag: Unconjugated

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Datasheets and Documentation

Product Datasheet

Certificate of Analysis and Tags (Coming Soon)

SKU: 28-MSM9-P1

Blood Group Antigen A General Information
Alternate Names
Histo-blood group ABO system transferase, ABO
Molecular Weight
Multiple
Chromosomal Location
9q34.2
Curated Database and Bioinformatic Data
Gene Symbol	ABO
Entrez Gene ID	28
Ensemble Gene ID	ENSG00000281879, ENSG00000175164
RefSeq Protein Accession(s)	NP_065202
RefSeq mRNA Accession(s)	NM_020469
RefSeq Genomic Accession(s)	NW_009646201, NG_006669, NC_018920, NC_000009
UniProt ID(s)	A0A089QDC1, P16442
UniGene ID(s)	A0A089QDC1, P16442
HGNC ID(s)	79
Cosmic ID(s)	ABO
KEGG Gene ID(s)	hsa:28
PharmGKB ID(s)	PA24415
General Description of Blood Group Antigen A.
This MAb preferably reacts with determinants of chain A, H type 3(Gal1-3GalNAc-R), 4 (Gal1-3GalNAc-R), but not with type 1, 2 chain structures. It is not reactive with immuno-dominant A trisaccharide. This MAb is applicable for tissue staining in tumor patients with blood groups A, AB. It shows a highly heterogeneous reactivity in human colon tumor tissue, adjacent mucosa. Blood-group antigens are generally defined as molecules formed by sequential addition of saccharides to the carbohydrate side chains of lipids, proteins detected on erythrocytes, certain epithelial cells. The A, B, H antigens are reported to undergo modulation during malignant cellular transformation. Blood group related antigens represent a group of carbohydrate determinants carried on both glycolipids, glycoproteins. They are usually mucin-type,, are detected on erythrocytes, certain epithelial cells,, in secretions of certain individuals. Sixteen genetically, biosynthetically distinct but inter-related specificities belong to this group of antigens, including A, B, H, Lewis A, Lewis B, Lewis X, Lewis Y,, precursor type 1 chain antigens.

Human Anti-Blood Group Antigen A Antibody Product Attributes

Species: Human

Tested Applications: Immunofluorescence, Immunohistochemistry (IHC).

Application Notes: Immunofluorescence (0.5-1ug of antibody/ml), Immunohistochemistry (IHC) (Formalin-fixed) (0.5-1.0ug of antibody/ml for 30 minutes at RT)

Clonality: Monoclonal

Anti-Blood Group Antigen A Antibody Clone: 3-3A

Clone 3-3A Host and Isotype: Mouse IgG1 kappa

Anti-Human Blood Group Antigen A Positive Control Sample: KG1 cells or human colorectal carcinoma tissues.

Cellular Localization of Antibody <3-3A Staining: Cell Surface

Buffer and Stabilizer: 10mM PBS with 0.05% BSA & 0.05% azide.

Antibody Concentration: 200ug/ml

Antibody Purification Method:Protein A/G Purified

Immunogen: Mucin isolated from an ovarian cyst fluid

Storage Conditions: Store at 2 to 8Â° C (refrigerate). Stable for 24 months when properly stored.

Blood Group Antigen A Previously Observed Antibody Staining Patterns

Limitations and Warranty

enQuire Bio's Blood Group Antigen A Anti-Human Monoclonal is available for Research Use Only. This antibody is guaranteed to work for a period of two years when properly stored.

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