Antibody (Suitable for clinical applications)
Sample Type: FFPE Patient Samples.
Tested Applications: IHC. Approved for In Vitro Diagnostic Procedures on FFPE tissues. For tissue collection recommendations, please see datasheet sent with product.
Application Notes
| Specification | Recommendation |
|---|---|
| Recommended Dilution (Conc) | 1:25-1:50 |
| Pretreatment | EDTA Buffer pH 8.0 |
| Incubation Parameters | 30 min at Room Temperature |
Prior to use, inspect vial for the presence of any precipitate or other unusual physical properties. These can indicate that the antibody has degraded and is no longer suitable for patient samples. Please run positive and negative controls simultaneously with all patient samples to account and control for errors in laboratory procedure. Use of methods or materials not recommended by enQuire Bio including change to dilution range and detection system should be routinely validated by the user.
Clonality: Monoclonal
Anti-c-myc Antibody Clone: 90000000000
Host and Isotype: Mouse IgG1
Recommended Positive Control Sample: Breast carcinoma
Cellular Localization of Antibody 90000000000 Staining: Nuclear
Buffer and Stabilizer: PBS with 1% BSA and 0.05% NaN3
Antibody Concentration: Lot specific. Plese contact tech support for data.
Immunogen: Synthetic peptide corresponding to residues 408-439 of the human p62c-myc protein.
Storage Conditions: This antibody should be stored refrigerated (2-8°C). This product should not be used past the expiration date printed on the vial.
c-myc Information for Pathologists
Summary:
Proto-oncogene at 8q24.1 produces short lived nuclear phosphoprotein. Overexpressed by t(8;14)(q24;q32.3), t(8;22);(q24;11) and t(2;8);(p11-12;q24), which translocate c-myc gene next to immunoglobulin genes in BurkittÂs lymphoma. Gene expressed in virtually all eukaryotic cells; expression usually tightly controlled. Immediate early growth response gene; rapidly induced when quiescent cells receive a signal to divide; required for cells to enter S phase.Limitations and Warranty
This antibody is manufactured in accordance with clinical good manufacturing practices in an ISO13485:2016 certified production facility. It is intended for multiple uses including in vitro diagnostic use and research use only applications. Please see vial label for expiration date. We strive to always deliver antibodies with a shelf life of at least two years.
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