Calcitonin [Polyclonal] Antibody (cGMP).

$ 145.00$ 445.00
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Species: Human
Tested Applications: IHC [IVD]
Available Conjugates:
Isotype: Rabbit Undetermined

Product NumberDescriptionPrice
QIVD80-0.1ml Size: 0.1 ml, Format: Concentrate $ 168.00
QIVD80-0.5ml Size: 0.5 ml, Format: Concentrate $ 298.00
QIVD80-1ml Size: 1 ml, Format: Concentrate $ 498.00
QIVD80-6ml Size: 6 ml, Format: Predilute $ 178.00
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Datasheets and Documentation
Product Datasheet
Certificate of Analysis and Tags (Coming Soon)
Lot Number:

Expiration Date:

Concentration (Write Lyophilized if Lyophilized):

Reconsitution Instructions (Leave Blank if Liquid):

Manufacture Date:


Bioactivity (test results eg. IU/ml):

SKU: QIVD80-0.1ml
Calcitonin General Information
Alternate Names
Molecular Weight
15.5 kDa
Chromosomal Location
p15.2 [chr: 11] [chr_start: 14966668] [chr_end: 14972354] [strand: -1]
Curated Database and Bioinformatic Data
Gene SymbolCALCA
Entrez Gene ID796
RefSeq Protein Accession(s)NP_001029124; NP_001732; XP_016873772; XP_016873773
RefSeq mRNA Accession(s); NM_001033953; NM_001741; NM_001033952; XM_017018284; NR_125898; XM_017018283
RefSeq Genomic Accession(s)NC_000011; NG_015960
UniProt ID(s)P01258
PharmGKB ID(s)PA26029
KEGG Gene ID(s)hsa:796
General Description of Calcitonin .
This antibody stains C cells of thyroid.

Antibody (Suitable for clinical applications)

Sample Type: FFPE Patient Samples.
Tested Applications: IHC. Approved for In Vitro Diagnostic Procedures on FFPE tissues. For tissue collection recommendations, please see datasheet sent with product.
Application Notes
Specification Recommendation
Recommended Dilution (Conc) 1:50-1:100
Pretreatment Citrate Buffer pH 6.0
Incubation Parameters 30 min at Room Temperature

Prior to use, inspect vial for the presence of any precipitate or other unusual physical properties. These can indicate that the antibody has degraded and is no longer suitable for patient samples. Please run positive and negative controls simultaneously with all patient samples to account and control for errors in laboratory procedure. Use of methods or materials not recommended by enQuire Bio including change to dilution range and detection system should be routinely validated by the user.

Clonality: Polyclonal
Anti-Calcitonin Antibody Clone: Polyclonal
Host and Isotype: Rabbit Undetermined
Recommended Positive Control Sample: Thyroid
Cellular Localization of Antibody Polyclonal Staining: Cytoplasmic
Buffer and Stabilizer: PBS with 1% BSA and 0.05% NaN3
Antibody Concentration: Lot specific. Plese contact tech support for data.
Immunogen: Synthetic peptide of human calcitonin corresponding to amino acids 1-32.
Storage Conditions: This antibody should be stored refrigerated (2-8°C). This product should not be used past the expiration date printed on the vial.

Calcitonin Information for Pathologists


Calcitonin (thyrocalcitonin) is a 32 amino acid linear polypeptide hormone (molecular weight 3,421Kd) that participates in calcium and phosphorus metabolism. It is formed by the proteolytic cleavage of a larger pre-propeptide, which is a product of the CALC1 gene (CALC). In humans, it is primarily produced by the parafollicular cells (C cells) of the thyroid. Other tissues such as the lungs and intestinal tract can also synthesize calcitonin. The calcitonin receptor protein has been shown to be a member of the seven transmembrane G protein coupled receptor family, which is coupled by G5 to adenylate cyclase and thereby to the generation of CAMP in target cells.

Common Uses By Pathologists:

As a marker for medullary thyroid carcinoma (MTC), especially when facing histologic subtypes such as the follicular, papillary or encapsulated variants that can pose diagnostic difficulties with follicular cell–derived carcinomas and paraganglioma (Arch Pathol Lab Med 2008;132:359). Although highly specific, calcitonin staining may be patchy in medullary carcinomas and 5% of these tumors may be negative for this marker. In tumors with no staining and still suspected to be MTC, calcitonin and calcitonin gene–related peptide mRNA can be demonstrated by in situ hybridization (Arch Pathol Lab Med 2010;134:207). To evaluate for C cell hyperplasia associated with familial MTC. High grade neuroendocrine tumors can also stain with calcitonin, and metastatic lesions can be misinterpreted as having arisen in the thyroid (Adv Anat Pathol 2004;11:202).

Limitations and Warranty

This antibody is manufactured in accordance with clinical good manufacturing practices in an ISO13485:2016 certified production facility. It is intended for multiple uses including in vitro diagnostic use and research use only applications. Please see vial label for expiration date. We strive to always deliver antibodies with a shelf life of at least two years.

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Calcitonin [Polyclonal] Antibody (cGMP).