Mouse Anti-CD115 / CSF1R / MCSF Receptor Antibody Product Attributes
Species: Mouse
Tested Applications: Flow Cytometry.
Application Notes: See Product Datasheet for Recommended Dilution Range. Requires Experimental Optimization
Clonality: Monoclonal Antibody
Anti-CD115 / CSF1R / MCSF Receptor Antibody Clone: AFS98
Clone AFS98 Host and Isotype: Rat IgG2a kappa
Buffer and Stabilizer: 10 mM NaH2PO4, 150 mM NaCl, 0.09% NaN3, 0.1% gelatin, pH7.2
Antibody Concentration: 0.2 mg/mL
Storage Conditions: 2-8C protected from light. Stable for 12 Months. Do Not Freeze.
CD115 / CSF1R / MCSF Receptor Previously Observed Antibody Staining Patterns
Observed Subcellular, Organelle Specific Staining Data:
Staining with anti-CD115 / CSF1R / MCSF Receptor antibody reveals CD115 / CSF1R / MCSF Receptor expression is expected to be primarily localized to the plasma membrane and vesicles.Observed Antibody Staining Data By Tissue Disease Status:
Tissues from cancer patients, for instance, have their own distinct pattern of CD115 / CSF1R / MCSF Receptor expression as measured by anti-CD115 / CSF1R / MCSF Receptor antibody immunohistochemical staining. The average level of expression by tumor is summarized in the table below. The variability row represents patient to patient variability in IHC staining.Sample Type | breast cancer | carcinoid | cervical cancer | colorectal cancer | endometrial cancer | glioma | head and neck cancer | liver cancer | lung cancer | lymphoma | melanoma | ovarian cancer | pancreatic cancer | prostate cancer | renal cancer | skin cancer | stomach cancer | testicular cancer | thyroid cancer | urothelial cancer |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
Signal Intensity | + | + | + | + | + | + | + | + | + | + | + | ++ | + | - | + | + | + | + | ++ | + |
CSF1R Variability | ++ | ++ | ++ | + | + | + | + | ++ | + | + | + | ++ | ++ | ++ | +++ | + | ++ | + | + | + |
Selected References
Gautier EL, Chow A, Spanbroek R, Marcelin G, Greter M, Jakubzick C, Bogunovic M, Leboeuf M, van Rooijen N, Habenicht AJ, Merad M, and Randolph GJ. 2012. J. Immunol. 189: 2614-2624. (Flow cytometry)Nakamichi Y, Mizoguchi T, Arai A, Kobayashi Y, Sato M, Penninger JM, Yasuda H, Kato, S, DeLuca HF, Suda T, Udagawa N, and Takahashi N. Proc. Natl. Acad. Sci. 109: 10006-10011. (in vitro blocking)Okuno Y, Nakamura-Ishizu A, Kishi K, Suda T, and Kubota Y. 2011. Blood. 117: 5264-5272. (in vivo blocking)Fixley FJ, Xiong Y, Yu R Y-L, Sahai EA, Stanley ER, and Ye BH. 2005. J. Cell Sci. 118: 1873-1883. (Western blot)
Limitations and Warranty
enQuire Bio's Mouse Anti-CD115 Monoclonal is available for Research Use Only. This antibody is guaranteed to work for a period of two years when properly stored.
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