Immunohistochemical staining of CD79a, B Cell  of human FFPE tissue followed by incubation with HRP labeled secondary and development with DAB substrate.

CD79a, B Cell [HM57] Antibody (cGMP).

$ 145.00$ 955.00
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Species: Human
Tested Applications: IHC [IVD]
Available Conjugates:
Isotype: Mouse IgG1, kappa

Product NumberDescriptionPrice
QIVD264-0.1ml Size: 0.1 ml, Format: Concentrate $ 145.00
QIVD264-0.5ml Size: 0.5 ml, Format: Concentrate $ 575.00
QIVD264-1ml Size: 1 ml, Format: Concentrate $ 955.00
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Datasheets and Documentation
Product Datasheet
Certificate of Analysis and Tags (Coming Soon)
Lot Number:

Expiration Date:

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Bioactivity (test results eg. IU/ml):

SKU: QIVD264-0.1ml
CD79a, B Cell General Information
Alternate Names
Molecular Weight
25 kDa
Chromosomal Location
q13.2 [chr: 19] [chr_start: 41877120] [chr_end: 41881372] [strand: 1]
Curated Database and Bioinformatic Data
Gene SymbolCD79A
Entrez Gene ID973
RefSeq Protein Accession(s)NP_067612; NP_001774
RefSeq mRNA Accession(s)NM_021601; NM_001783;
RefSeq Genomic Accession(s)NG_009619; NC_000019
UniProt ID(s)P11912
PharmGKB ID(s)PA26237
KEGG Gene ID(s)hsa:973
Associated Diseases (KEGG IDs)Agammaglobulinemia 3, autosomal recessive (AGM3) [MIM:613501]: A primary immunodeficiency characterized by profoundly low or absent serum antibodies and low or absent circulating B-cells due to an early block of B-cell development. Affected individuals develop severe infections in the first years of life. {ECO:0000269|PubMed:10525050, ECO:0000269|PubMed:11920841}. The disease is caused by mutations affecting the gene represented in this entry. Two different mutations, one at the splice donor site of intron 2 and the other at the splice acceptor site for exon 3, have been identified. Both mutations give rise to a truncated protein.
General Description of CD79a, B Cell .
This antibody reacts specifically with B cells at the pre B cell stage. It stains a majority of acute leukemias of precursor B cell type, B cell lymphomas and some myelomas. The mb-1 polypeptide along with B29 polypeptide forms an antigen receptor complex on the B cell, performing signal transduction and phosphorylation functions.

Antibody (Suitable for clinical applications)

Sample Type: FFPE Patient Samples.
Tested Applications: IHC. Approved for In Vitro Diagnostic Procedures on FFPE tissues. For tissue collection recommendations, please see datasheet sent with product.
Application Notes
Specification Recommendation
Recommended Dilution (Conc) 1:30-1:60
Pretreatment Citrate Buffer pH 6.0
Incubation Parameters 30 min at Room Temperature

Prior to use, inspect vial for the presence of any precipitate or other unusual physical properties. These can indicate that the antibody has degraded and is no longer suitable for patient samples. Please run positive and negative controls simultaneously with all patient samples to account and control for errors in laboratory procedure. Use of methods or materials not recommended by enQuire Bio including change to dilution range and detection system should be routinely validated by the user.

Clonality: Monoclonal
Anti-CD79a, B Cell Antibody Clone: HM57
Host and Isotype: Mouse IgG1, kappa
Recommended Positive Control Sample: Tonsil
Cellular Localization of Antibody HM57 Staining: Cell membrane
Buffer and Stabilizer: PBS with 1% BSA and 0.05% NaN3
Antibody Concentration: Lot specific. Plese contact tech support for data.
Immunogen: Synthetic peptide comprising of 202-216 C terminal amino acids part of mb-1 protein.
Storage Conditions: This antibody should be stored refrigerated (2-8°C). This product should not be used past the expiration date printed on the vial.

CD79a, B Cell Information for Pathologists

Limitations and Warranty

This antibody is manufactured in accordance with clinical good manufacturing practices in an ISO13485:2016 certified production facility. It is intended for multiple uses including in vitro diagnostic use and research use only applications. Please see vial label for expiration date. We strive to always deliver antibodies with a shelf life of at least two years.

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CD79a, B Cell [HM57] Antibody (cGMP).