Immunohistochemical staining of CD79a of human FFPE tissue followed by incubation with HRP labeled secondary and development with DAB substrate.

CD79a [HM47/A9] Antibody (cGMP).

Name: CD79a [HM47/A9] Antibody (cGMP).
Brand: enQuire Bio
Price: 135 USD
Availability: InStock

$ 135.00 – $ 855.00

Please Select Product Options Below To View The Catalog Number.

SKU: QIVD55
Species: Human
Tested Applications: IHC [IVD]
Available Conjugates:
Isotype: Mouse IgG1, kappa

Product Number	Description	Price
QIVD55-0.1ml	Size: 0.1 ml, Format: Concentrate	$ 135.00
QIVD55-0.5ml	Size: 0.5 ml, Format: Concentrate	$ 505.00
QIVD55-1ml	Size: 1 ml, Format: Concentrate	$ 855.00

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In Stock

Flat Rate Shipping Anywhere in the US: $45

Datasheets and Documentation

Product Datasheet

Certificate of Analysis and Tags (Coming Soon)

SKU: QIVD55-0.1ml

CD79a General Information
Alternate Names

Molecular Weight
25 kDa
Chromosomal Location
q13.2 [chr: 19] [chr_start: 41877120] [chr_end: 41881372] [strand: 1]
Curated Database and Bioinformatic Data
Gene Symbol	CD79A
Entrez Gene ID	973
RefSeq Protein Accession(s)	NP_067612; NP_001774
RefSeq mRNA Accession(s)	NM_021601; NM_001783;
RefSeq Genomic Accession(s)	NG_009619; NC_000019
UniProt ID(s)	P11912
PharmGKB ID(s)	PA26237
KEGG Gene ID(s)	hsa:973
Associated Diseases (KEGG IDs)	Agammaglobulinemia 3, autosomal recessive (AGM3) [MIM:613501]: A primary immunodeficiency characterized by profoundly low or absent serum antibodies and low or absent circulating B-cells due to an early block of B-cell development. Affected individuals develop severe infections in the first years of life. {ECO:0000269\|PubMed:10525050, ECO:0000269\|PubMed:11920841}. The disease is caused by mutations affecting the gene represented in this entry. Two different mutations, one at the splice donor site of intron 2 and the other at the splice acceptor site for exon 3, have been identified. Both mutations give rise to a truncated protein.
General Description of CD79a .
This antibody is specific to human CD79a antigen complex, consisting of two polypeptides non-covalently associated with membrane-bound immunoglobulins on B cells. This complex of polypeptide and immunoglobulins constitute the B cell antigen receptor. The two components of this complex are designated CD79a and CD79b. The CD79a antigen appears at the pre-B cell stage, early in maturation and persists until the plasma cell stage. The CD79a antigen is found in majority of acute leukemias of precursor B cell type, in B cell lines and B cell lymphomas.

Antibody (Suitable for clinical applications)

Sample Type: FFPE Patient Samples.

Tested Applications: IHC. Approved for In Vitro Diagnostic Procedures on FFPE tissues. For tissue collection recommendations, please see datasheet sent with product.

Application Notes

Specification	Recommendation
Recommended Dilution (Conc)	1:50-1:100
Pretreatment	EDTA Buffer pH 8.0
Incubation Parameters	30 min at Room Temperature

Prior to use, inspect vial for the presence of any precipitate or other unusual physical properties. These can indicate that the antibody has degraded and is no longer suitable for patient samples. Please run positive and negative controls simultaneously with all patient samples to account and control for errors in laboratory procedure. Use of methods or materials not recommended by enQuire Bio including change to dilution range and detection system should be routinely validated by the user.

Clonality: Monoclonal

Anti-CD79a Antibody Clone: HM47/A9

Host and Isotype: Mouse IgG1, kappa

Recommended Positive Control Sample: Tonsil

Cellular Localization of Antibody HM47/A9 Staining: Cell membrane

Buffer and Stabilizer: PBS with 1% BSA and 0.05% NaN₃

Antibody Concentration: Lot specific. Plese contact tech support for data.

Immunogen: Synthetic polypeptide consisting of the amino acid sequence GTYQDVGSLNIADVQ.

Storage Conditions: This antibody should be stored refrigerated (2-8°C). This product should not be used past the expiration date printed on the vial.

CD79a Information for Pathologists

Limitations and Warranty

This antibody is manufactured in accordance with clinical good manufacturing practices in an ISO13485:2016 certified production facility. It is intended for multiple uses including in vitro diagnostic use and research use only applications. Please see vial label for expiration date. We strive to always deliver antibodies with a shelf life of at least two years.

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