Formalin-fixed, paraffin-embedded Human Pancreas stained with Clathrin, LC Monoclonal Antibody (CLC/1421).
Formalin-fixed, paraffin-embedded Human Pancreas stained with Clathrin, LC Monoclonal Antibody (CLC/1421).

Anti-Clathrin, Light Chain Antibody Clone CLC/1421

$ 118.00$ 418.00
Please Select Product Options Below To View The Catalog Number.

SKU: 1211-MSM1
Species: Human
Tested Applications: Immunohistochemistry (IHC)
Available Conjugates: Unconjugated
Isotype: Mouse IgG2b kappa
Mass Spec Validated?: Not MS Validated

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Datasheets and Documentation
Product Datasheet
SKU: 1211-MSM1-P0
Clathrin, Light Chain General Information
Alternate Names
Serum amyloid A1, SAA1, SAA1
Molecular Weight
31-44kDa
Chromosomal Location
9p13.3
Curated Database and Bioinformatic Data
Gene SymbolCLTA and CLTB
Entrez Gene ID1211, 1212
Ensemble Gene IDENSG00000122705, ENSG00000175416
RefSeq Protein Accession(s)NP_001070145, NP_001298132, NP_001171690, XP_016869747, NP_001171689, NP_001298133, NP_001298135, XP_016869746, NP_001298134, NP_009027, NP_001171691, NP_001824, NP_001825, XP_016864516, NP_009028, XP_016864515
RefSeq mRNA Accession(s)XM_017014257, NM_001311204, NM_001076677, NM_001184762, NR_132349, NM_001184760, NM_001311203, NM_001311205, NM_001311206, XM_017014258, NM_001184761, NM_001833, NM_007096, XR_001741996, NM_007097, NM_001834, XM_017009026, XM_017009027, XR_001741995, NR_045724
RefSeq Genomic Accession(s)NC_018920, NC_000009NC_018916, NC_000005
UniProt ID(s)P09496, C9J8P9, B4DTF9, A0A024R7S3, 90497
UniGene ID(s)P09496, C9J8P9, B4DTF9, A0A024R7S3, 90497
HGNC ID(s)2090, 2091
Cosmic ID(s)CLTA, CLTB
KEGG Gene ID(s)hsa:1211, hsa:1212
PharmGKB ID(s)PA26616, PA26617
General Description of Clathrin, Light Chain.
Recognizes proteins of 31-44kDa, which are identified as Clathrin Light Chains (both A ;B). Clathrin is composed of three heavy chains and three light chains, which associate non-covalently to form a triskelion structure. Clathrin light chain regulates the self-assembly of triskelions onto intracellular membranes. Clathrin light chain subunits (LCA and LCB) contribute to regulation of coated vesicle formation to sort proteins during receptor-mediated endocytosis and organelle biogenesis. LCA and LCB are encoded by two discrete genes. They share only 60% homology, and have certain features in common. Both LCA and LCB undergo alternative mRNA splicing, which results in the generation of tissue-specific isoforms.

Human Anti-Clathrin, Light Chain Antibody Product Attributes

Species: Human
Tested Applications: Immunohistochemistry (IHC).
Clonality: Monoclonal
Anti-Clathrin, Light Chain Antibody Clone: CLC/1421
Clone CLC/1421 Host and Isotype: Mouse IgG2b kappa
Anti-Human Clathrin, Light Chain Positive Control Sample: HeLa cells. Placenta or Prostate Carcinoma.
Cellular Localization of Antibody Cytoplasmic
Buffer and Stabilizer: 10mM PBS with 0.05% BSA and 0.05% Azide
Antibody Concentration: 200 ug/ml
Antibody Purification Method:Protein A/G Purified
Immunogen: Purified recombinant N-terminal fragment of human Clathrin Light Chain
Storage Conditions: Store at 2 to 8° C (refrigerate). Stable for 24 months when properly stored.

Clathrin, Light Chain Previously Observed Antibody Staining Patterns

Observed Subcellular, Organelle Specific Staining Data:

Anti-CLTA and CLTB antibody staining is expected to be primarily localized to the endosomes and lysosomes.

Limitations and Warranty

enQuire Bio's Clathrin, Light Chain Anti-Human Monoclonal is available for Research Use Only. This antibody is guaranteed to work for a period of two years when properly stored.

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