Immunohistochemical staining of Cyclin E Protein  of human FFPE tissue followed by incubation with HRP labeled secondary and development with DAB substrate.

Cyclin E Protein [HE12] Antibody (cGMP).

$ 158.00$ 858.00
Please Select Product Options Below To View The Catalog Number.

Species: Human
Tested Applications: IHC [IVD]
Available Conjugates:
Isotype: Mouse IgG1

Product NumberDescriptionPrice
QIVD265-0.1ml Size: 0.1 ml, Format: Concentrate $ 135.00
QIVD265-1ml Size: 1 ml, Format: Concentrate $ 765.00
QIVD265-6ml Size: 6 ml, Format: Predilute $ 345.00
QIVD265-0.5ml0.5ml Size: 0.5ml, Format: Predilute $ 455.00
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Datasheets and Documentation
Product Datasheet
Certificate of Analysis and Tags (Coming Soon)
Lot Number:

Expiration Date:

Concentration (Write Lyophilized if Lyophilized):

Reconsitution Instructions (Leave Blank if Liquid):

Manufacture Date:


Bioactivity (test results eg. IU/ml):

SKU: QIVD265-0.1ml
Cyclin E Protein General Information
Alternate Names
Molecular Weight
47.1 kDa
Chromosomal Location
q12 [chr: 19] [chr_start: 29811991] [chr_end: 29824312] [strand: 1]
Curated Database and Bioinformatic Data
Gene SymbolCCNE1
Entrez Gene ID898
RefSeq Protein Accession(s)NP_001229; NP_001309191
RefSeq mRNA Accession(s)NM_001238; NM_057182; NM_001322262; XM_011527440; NM_001322259; NM_001322261
RefSeq Genomic Accession(s)NC_000019;
UniProt ID(s)P24864
PharmGKB ID(s)PA96
KEGG Gene ID(s)hsa:898
General Description of Cyclin E Protein .
This antibody recognizes a doublet of 50 kDa and a single band of 42 kDa identified as cyclin E. Cyclin proteins are a family of related proteins, which control the progression of the eukaryotic cell cycle. Overexpression of cyclin E shortens the length of the G1 phase, accelerating progression of S phase. The activity of cyclin E is mediated through its activation of cyclin dependent kinase 2 (cdk2) protein and is modulated by the presence of tumor suppressor proteins such as p16.

Antibody (Suitable for clinical applications)

Sample Type: FFPE Patient Samples.
Tested Applications: IHC. Approved for In Vitro Diagnostic Procedures on FFPE tissues. For tissue collection recommendations, please see datasheet sent with product.
Application Notes
Specification Recommendation
Recommended Dilution (Conc) 1:100-1:200
Pretreatment EDTA Buffer pH 8.0
Incubation Parameters 30 min at Room Temperature

Prior to use, inspect vial for the presence of any precipitate or other unusual physical properties. These can indicate that the antibody has degraded and is no longer suitable for patient samples. Please run positive and negative controls simultaneously with all patient samples to account and control for errors in laboratory procedure. Use of methods or materials not recommended by enQuire Bio including change to dilution range and detection system should be routinely validated by the user.

Clonality: Monoclonal
Anti-Cyclin E Protein Antibody Clone: HE12
Host and Isotype: Mouse IgG1
Recommended Positive Control Sample: Breast carcinoma
Cellular Localization of Antibody HE12 Staining: Nuclear
Buffer and Stabilizer: PBS with 1% BSA and 0.05% NaN3
Antibody Concentration: Lot specific. Plese contact tech support for data.
Immunogen: Synthetic peptide corresponding to human cyclin E protein.
Storage Conditions: This antibody should be stored refrigerated (2-8°C). This product should not be used past the expiration date printed on the vial.

Cyclin E Protein Information for Pathologists

Limitations and Warranty

This antibody is manufactured in accordance with clinical good manufacturing practices in an ISO13485:2016 certified production facility. It is intended for multiple uses including in vitro diagnostic use and research use only applications. Please see vial label for expiration date. We strive to always deliver antibodies with a shelf life of at least two years.

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Cyclin E Protein [HE12] Antibody (cGMP).