Immunohistochemical staining of Cytokeratin 8, Low Molecular Weight  of human FFPE tissue followed by incubation with HRP labeled secondary and development with DAB substrate.

Cytokeratin 8, Low Molecular Weight [35betaH11] Antibody (cGMP).

$ 135.00$ 485.00
Please Select Product Options Below To View The Catalog Number.

SKU: QIVD275
Species: Human
Tested Applications: IHC [IVD]
Available Conjugates:
Isotype: Mouse IgM, kappa

Product NumberDescriptionPrice
QIVD275-0.1ml Size: 0.1 ml, Format: Concentrate $ 135.00
QIVD275-0.5ml Size: 0.5 ml, Format: Concentrate $ 285.00
QIVD275-1ml Size: 1 ml, Format: Concentrate $ 485.00
QIVD275-6ml Size: 6 ml, Format: Predilute $ 205.00
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SKU: QIVD275-0.1ml
Cytokeratin 8, Low Molecular Weight General Information
Alternate Names
Molecular Weight
53.7 kDa
Chromosomal Location
q13.13 [chr: 12] [chr_start: 52897187] [chr_end: 52949954] [strand: -1]
Curated Database and Bioinformatic Data
Gene SymbolKRT8
Entrez Gene ID3856
RefSeq Protein Accession(s)NP_002264; NP_001243222
RefSeq mRNA Accession(s)NR_045962; NM_001256282; NM_001256293; NM_002273
RefSeq Genomic Accession(s)NC_000012; NG_008402
UniProt ID(s)P05787
PharmGKB ID(s)PA30234
KEGG Gene ID(s)hsa:3856
Associated Diseases (KEGG IDs)Cirrhosis (CIRRH) [MIM:215600]: A liver disease characterized by severe panlobular liver-cell swelling with Mallory body formation, prominent pericellular fibrosis, and marked deposits of copper. Clinical features include abdomen swelling, jaundice and pulmonary hypertension. {ECO:0000269|PubMed:12724528}. The disease is caused by mutations affecting the gene represented in this entry.
General Description of Cytokeratin 8, Low Molecular Weight .
This antibody recognizes keratin polypeptide of 54 kDa. It stains strongly with non-squamous epithelium but does not stain squamous epithelium. It reacts with the sweat gland and ducts in the skin. Adenocarcinomas of the ovary, gastrointestinal tract, ductal carcinoma of breast, pancreas and bile ducts, stain positive with this antibody.

Antibody (Suitable for clinical applications)

Sample Type: FFPE Patient Samples.
Tested Applications: IHC. Approved for In Vitro Diagnostic Procedures on FFPE tissues. For tissue collection recommendations, please see datasheet sent with product.
Application Notes
Specification Recommendation
Recommended Dilution (Conc) 1:25-1:50
Pretreatment HistoZyme
Incubation Parameters 30 min at Room Temperature

Prior to use, inspect vial for the presence of any precipitate or other unusual physical properties. These can indicate that the antibody has degraded and is no longer suitable for patient samples. Please run positive and negative controls simultaneously with all patient samples to account and control for errors in laboratory procedure. Use of methods or materials not recommended by enQuire Bio including change to dilution range and detection system should be routinely validated by the user.

Clonality: Monoclonal
Anti-Cytokeratin 8, Low Molecular Weight Antibody Clone: 35betaH11
Host and Isotype: Mouse IgM, kappa
Recommended Positive Control Sample: Skin, Colon
Cellular Localization of Antibody 35betaH11 Staining: Cytoplasmic
Buffer and Stabilizer: PBS with 1% BSA and 0.05% NaN3
Antibody Concentration: Lot specific. Plese contact tech support for data.
Immunogen: BALB/C mice were immunized with cytoskeletal extract of human hepatocellular carcinoma cell line, Hep3B.
Storage Conditions: This antibody should be stored refrigerated (2-8°C). This product should not be used past the expiration date printed on the vial.

Cytokeratin 8, Low Molecular Weight Information for Pathologists

Limitations and Warranty

This antibody is manufactured in accordance with clinical good manufacturing practices in an ISO13485:2016 certified production facility. It is intended for multiple uses including in vitro diagnostic use and research use only applications. Please see vial label for expiration date. We strive to always deliver antibodies with a shelf life of at least two years.

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Cytokeratin 8, Low Molecular Weight [35betaH11] Antibody (cGMP).