Formalin paraffin Rat Stomach stained with Cytokeratin, pan Monoclonal Antibody cocktail (KRTL/177 + KRTH/176).

Formalin-fixed, paraffin-embedded Rat Oviduct with Cytokeratin, pan Monoclonal Antibody cocktail (KRTL/177 + KRTH/176).

Anti-Cytokeratin Antibody Clone KRTL/1077 + KRTH/1076

Name: Anti-Cytokeratin Antibody Clone KRTL/1077 + KRTH/1076
Brand: enQuire Bio
Price: 429 USD
Availability: InStock

$ 429.00

Please Select Product Options Below To View The Catalog Number.

SKU: MSM10-1100
Species: Human, Rat, and Broad Species Reactivity
Tested Applications: Flow Cytometry, Immunofluorescence, Immunohistochemistry (IHC)
Available Conjugates: Unconjugated
Isotype: Mouse IgG
Mass Spec Validated?: Not MS Validated

Product Number	Description	Price
MSM10-1100-P1	Size: 100 ug, Tag: Unconjugated

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In Stock.

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Datasheets and Documentation

Product Datasheet

Certificate of Analysis and Tags (Coming Soon)

SKU: MSM10-1100-P1

Cytokeratin General Information
Molecular Weight
67kDa (CK1); 64kDa (CK3); 59kDa (CK4); 58kDa (CK5); 56kDa (CK6); 52kDa (CK8); 56.5kDa (CK10); 50kDa (CK14); 50kDa (CK15); 48kDa (CK16); 40kDa (CK19)
Curated Database and Bioinformatic Data
Entrez Gene ID	374454, 51350
Ensemble Gene ID	ENSG00000189182, ENSG00000185069
RefSeq Protein Accession(s)	NP_778253, XP_011536591, XP_011536590, NP_056932
RefSeq mRNA Accession(s)	XM_011538288, NM_175078 NM_015848,
RefSeq Genomic Accession(s)	NC_000012, NC_018923, NG_012322, NG_012420, NC_000012, NC_018923
UniProt ID(s)	Q7Z794, Q0IIN1, Q01546
UniGene ID(s)	Q7Z794, Q0IIN1, Q01546
HGNC ID(s)	20411, 24430
Cosmic ID(s)	KRT77, KRT76
KEGG Gene ID(s)	hsa:374454, hsa:51350
PharmGKB ID(s)	PA134896049, PA147357785
General Description of Cytokeratin.
Twenty human keratins are resolved with two-dimensional gel electrophoresis into acidic (pI 6.0) subfamilies. This antibody cocktail recognizes acidic (Type I or LMW), basic (Type II or HMW) cytokeratins, which include CK1, CK3, CK4, CK5, CK6, CK8, CK10, CK14, CK15, CK16,, CK19. Many studies have shown the usefulness of keratins as markers in cancer research, tumor diagnosis. KRTL/KRTH is a broad spectrum anti pan-cytokeratin antibody cocktail, which differentiates epithelial tumors from non-epithelial tumors e.g. squamous vs. adenocarcinoma of the lung, liver carcinoma, breast cancer,, esophageal cancer. It has been used to characterize the source of various neoplasms, to study the distribution of cytokeratin containing cells in epithelia during normal development, during the development of epithelial neoplasms. This antibody stains cytokeratins present in normal, abnormal human tissues, has shown high sensitivity in the recognition of epithelial cells, carcinomas.

Human, Rat, and Broad Species Reactivity Anti-Cytokeratin Antibody Product Attributes

Species: Human, Rat, and Broad Species Reactivity

Tested Applications: Flow Cytometry, Immunofluorescence, Immunohistochemistry (IHC).

Application Notes: Flow Cytometry (0.5-1ug of antibody/million cells in 0.1ml), Immunofluorescence (1-2ug of antibody/ml), Immunohistochemistry (IHC) (Formalin-fixed) (0.25-0.5ug of antibody/ml for 30 min at RT)

Clonality: Monoclonal

Anti-Cytokeratin Antibody Clone: KRTL/1077 + KRTH/1076

Clone KRTL/1077 + KRTH/1076 Host and Isotype: Mouse IgG

Anti-Human, Rat, and Broad Species Reactivity Cytokeratin Positive Control Sample: Skin, Adeno- or Squamous carcinomas

Cellular Localization of Antibody Cytoplasmic

Buffer and Stabilizer: 10mM PBS with 0.05% BSA & 0.05% azide.

Antibody Concentration: 200ug/ml

Antibody Purification Method:Protein A/G Purified

Immunogen: Recombinant human KRT77, KRT76 protein

Storage Conditions: Store at 2 to 8Â° C (refrigerate). Stable for 24 months when properly stored.

Cytokeratin Previously Observed Antibody Staining Patterns

Limitations and Warranty

enQuire Bio's Cytokeratin, pan Anti-Human, Rat Monoclonal is available for Research Use Only. This antibody is guaranteed to work for a period of two years when properly stored.

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