Human Anti-ETS1 Antibody Product Attributes
Species: Human
Tested Applications: Immunohistochemistry (IHC).
Clonality: Monoclonal
Anti-ETS1 Antibody Clone: ETS1/1282
Clone ETS1/1282 Host and Isotype: Mouse IgG
Anti-Human ETS1 Positive Control Sample: HepG2 and HeLa cells. Tonsil, Skin, Pancreas, Kidney and Lymphoma.
Cellular Localization of Antibody Nuclear
Buffer and Stabilizer: 10mM PBS with 0.05% BSA and 0.05% Azide
Antibody Concentration: 200 ug/ml
Antibody Purification Method:Protein A/G Purified
Immunogen: Recombinant human ETS1 fragment (aa137-230)
Storage Conditions: Store at 2 to 8° C (refrigerate). Stable for 24 months when properly stored.
ETS1 Previously Observed Antibody Staining Patterns
Observed Subcellular, Organelle Specific Staining Data:
Anti-ETS1 antibody staining is expected to be primarily localized to the nucleoplasm. There is variability in either the signal strength or the localization of signal in nucleoplasm from cell to cell.Observed Antibody Staining Data By Tissue Type:
Variations in ETS1 antibody staining intensity in immunohistochemistry on tissue sections are present across different anatomical locations. An intense signal was observed in germinal center cells in the tonsil, hematopoietic cells in the bone marrow, lymphoid tissue in appendix and non-germinal center cells in the lymph node and tonsil. More moderate antibody staining intensity was present in germinal center cells in the tonsil, hematopoietic cells in the bone marrow, lymphoid tissue in appendix and non-germinal center cells in the lymph node and tonsil. Low, but measureable presence of ETS1 could be seen in. We were unable to detect ETS1 in other tissues. Disease states, inflammation, and other physiological changes can have a substantial impact on antibody staining patterns. These measurements were all taken in tissues deemed normal or from patients without known disease.Observed Antibody Staining Data By Tissue Disease Status:
Tissues from cancer patients, for instance, have their own distinct pattern of ETS1 expression as measured by anti-ETS1 antibody immunohistochemical staining. The average level of expression by tumor is summarized in the table below. The variability row represents patient to patient variability in IHC staining.| Sample Type | breast cancer | carcinoid | cervical cancer | colorectal cancer | endometrial cancer | glioma | head and neck cancer | liver cancer | lung cancer | lymphoma | melanoma | ovarian cancer | pancreatic cancer | prostate cancer | renal cancer | skin cancer | stomach cancer | testicular cancer | thyroid cancer | urothelial cancer |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Signal Intensity | - | - | - | - | - | - | - | - | - | ++ | + | - | - | - | - | - | - | - | - | - |
| ETS1 Variability | + | + | + | + | + | + | + | + | + | ++ | ++ | + | + | + | + | + | + | + | + | + |
Limitations and Warranty
enQuire Bio's ETS1 Anti-Human Monoclonal is available for Research Use Only. This antibody is guaranteed to work for a period of two years when properly stored.
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