Tested Applications: ELISA,CLIA, LFIA (Lateral Flow Immunoassay).
Anti-Ferritin Light Chain Antibody Clone: FTL-Q4
Clone FTL-Q4 Host and Isotype: Mouse IgG2b
Buffer and Stabilizer: PBS (pH 7.4)
Antibody Purification Method:Protein G
Storage Conditions: Upon receipt aliquot and store at -20C or -80C. Avoid repeated freeze.
Ferritin Light Chain Previously Observed Antibody Staining Patterns
Observed Subcellular, Organelle Specific Staining Data:
Anti-FTL antibody staining is expected to be primarily localized to cytosol.
Observed Antibody Staining Data By Tissue Type:
Variations in Ferritin Light Chain antibody staining intensity in immunohistochemistry on tissue sections are present across different anatomical locations. An intense signal was observed in cells in tubules in kidney, glial cells in caudate nucleus and cerebral cortex, hepatocytes in liver, Leydig cells in testis, macrophages in lung, neuronal cells in caudate nucleus, Purkinje cells in cerebellum. More moderate antibody staining intensity was present in bile duct cells in liver, cells in endometrial stroma in endometrium, cells in molecular layer in cerebellum, cells in red pulp in spleen, epidermal cells in skin, germinal center cells in lymph node and tonsil, glandular cells in gallbladder and parathyroid gland and small intestine and stomach, glial cells in hippocampus, hematopoietic cells in bone marrow, islets of Langerhans in pancreas, keratinocytes in skin, lymphoid tissue in appendix, melanocytes in skin, neuropil in cerebral cortex, non-germinal center cells in lymph node and tonsil, respiratory epithelial cells in bronchus, squamous epithelial cells in esophagus and vagina. Low, but measureable presence of Ferritin Light Chain could be seen in cells in endometrial stroma in endometrium, cells in seminiferous ducts in testis, exocrine glandular cells in pancreas, fibroblasts in skin and mesenchymal tissue, glandular cells in breast and endometrium and epididymis and prostate and salivary gland and stomach and thyroid gland, Langerhans in skin, myocytes in heart muscle, neuronal cells in cerebral cortex and hippocampus, respiratory epithelial cells in nasopharynx, smooth muscle cells in smooth muscle, squamous epithelial cells in cervix, uterine and oral mucosa and tonsil, trophoblastic cells in placenta, urothelial cells in urinary bladder. We were unable to detect Ferritin Light Chain in other tissues. Disease states, inflammation, and other physiological changes can have a substantial impact on antibody staining patterns. These measurements were all taken in tissues deemed normal or from patients without known disease.
Limitations and Warranty
This product is for research use only. This product is not approved for use in diagnostics or therapeutics. The product is guaranteed for a period of two years, if stored under the specified conditions.