Human Anti-Filaggrin Antibody Product Attributes
Tested Applications: Immunohistochemistry (IHC).
Anti-Filaggrin Antibody Clone: FLG/1561
Clone FLG/1561 Host and Isotype: Mouse IgG1
Anti-Human Filaggrin Positive Control Sample: U-251-MG cells or Skin
Cellular Localization of Antibody Cytoplasmic
Buffer and Stabilizer: 10mM PBS with 0.05% BSA and 0.05% Azide
Antibody Concentration: 200 ug/ml
Antibody Purification Method:Protein A/G Purified
Immunogen: Recombinant human Filaggrin protein fragment (aa 998-1104)
Storage Conditions: Store at 2 to 8Â° C (refrigerate). Stable for 24 months when properly stored.
Filaggrin Previously Observed Antibody Staining Patterns
Observed Subcellular, Organelle Specific Staining Data:
Anti-FLG antibody staining is expected to be primarily localized to the vesicles.
Observed Antibody Staining Data By Tissue Type:
Variations in Filaggrin antibody staining intensity in immunohistochemistry on tissue sections are present across different anatomical locations. An intense signal was observed in epidermal cells in the skin. More moderate antibody staining intensity was present in epidermal cells in the skin. Low, but measureable presence of Filaggrin could be seen infibroblasts in skin, melanocytes in skin, squamous epithelial cells in the cervix and uterine. We were unable to detect Filaggrin in other tissues. Disease states, inflammation, and other physiological changes can have a substantial impact on antibody staining patterns. These measurements were all taken in tissues deemed normal or from patients without known disease.
Limitations and Warranty
enQuire Bio's Filaggrin Anti-Human Monoclonal is available for Research Use Only. This antibody is guaranteed to work for a period of two years when properly stored.