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Western Blot of THP1 and Raji Cell Lysate using FLI1 Monoclonal Antibody (FLI1/1312)
Western Blot of THP1 and Raji Cell Lysate using FLI1 Monoclonal Antibody (FLI1/1312)

Anti-FLI1 Antibody Clone FLI1/1312

$ 228.00 – $ 518.00
Please Select Product Options Below To View The Catalog Number.

SKU: 2313-MSM2
Species: Human
Tested Applications: Western Blot
Available Conjugates: Unconjugated
Isotype: Mouse IgG
Mass Spec Validated?: Not MS Validated

Product NumberDescriptionPrice
2313-MSM2-P0 Size: 20 ug, Tag: Unconjugated $ 228.00
2313-MSM2-P1 Size: 100 ug, Tag: Unconjugated $ 488.00
2313-MSM2-P2 Size: 200 ug, Tag: Unconjugated $ 518.00
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In Stock.
Flat Rate Shipping Anywhere in the US: $45
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SKU: 2313-MSM2-P0
FLI1 General Information
Alternate Names
Friend leukemia integration 1 transcription factor, FLI1, transcription factor ERGB,
Molecular Weight
51kDa
Chromosomal Location
11q24.1-q24.3
Curated Database and Bioinformatic Data
Gene SymbolFLI1
Entrez Gene ID2313
Ensemble Gene IDENSG00000151702
RefSeq Protein Accession(s)NP_001257941, XP_011541004, XP_016872895, XP_016872894, NP_001257939, NP_002008, XP_011541003, NP_001161153
RefSeq mRNA Accession(s)XM_011542701, XM_017017406 NM_001271012, NM_001271010, NM_002017, XM_011542702, XM_017017405, NM_001167681
RefSeq Genomic Accession(s)NC_000011, NC_018922, NG_032912
UniProt ID(s)A0A024R3K4, A0A024R3M5, A0A024R3N6, Q01543
UniGene ID(s)A0A024R3K4, A0A024R3M5, A0A024R3N6, Q01543
HGNC ID(s)3749
Cosmic ID(s)FLI1
KEGG Gene ID(s)hsa:2313
PharmGKB ID(s)PA28170
General Description of FLI1.
Recognizes a protein of 51kDa, which is identified as FLI1. This protein, a member of the ETS family of DNA binding transcription factors, is involved in cellular proliferation and tumorigenesis. Ets-1 is the prototype member of a family of genes identified on the basis of homology to the v-Ets oncogene isolated from the E26 erythroblastosis virus.Members of the Ets gene family share a highly conserved carboxy-terminal domain containing a sequence related to the SV40 large T antigen nuclear localization signal sequence. Approximately 90% of Ewing s Sarcoma (EWS) / Primitive Neuroectodermal Tumors (PNET) have a specific translocation, t(11;22)(q24;q12), which results in fusion of EWS to Fli-1, and production of an EWS-Fli-1 fusion protein. Among normal tissues only endothelial cells and small lymphocytes express Fli-1. This protein is expressed in majority of vascular tumors including angiosarcomas, hemangioendotheliomas, hemangiomas, and Kaposi s Sarcomas. High sensitivity and specificity of Fli-1 equals to or exceeds that of the established vascular markers like CD31, CD34, and Factor VIII.

Human Anti-FLI1 Antibody Product Attributes

Species: Human
Tested Applications: Western Blot.
Clonality: Monoclonal
Anti-FLI1 Antibody Clone: FLI1/1312
Clone FLI1/1312 Host and Isotype: Mouse IgG
Anti-Human FLI1 Positive Control Sample: THP1 and Raji cells. Tonsil, Ewing s sarcoma (EWS) and Angiosarcoma
Cellular Localization of Antibody Nuclear
Buffer and Stabilizer: 10mM PBS with 0.05% BSA and 0.05% Azide
Antibody Concentration: 200 ug/ml
Antibody Purification Method:Protein A/G Purified
Immunogen: Recombinant fragment (aa 107-261) of human FLI1 protein
Storage Conditions: Store at 2 to 8° C (refrigerate). Stable for 24 months when properly stored.

FLI1 Previously Observed Antibody Staining Patterns

Observed Subcellular, Organelle Specific Staining Data:

Anti-FLI1 antibody staining is expected to be primarily localized to the nuclear bodies and nucleus. There is variability in either the signal strength or the localization of signal in nuclear bodies from cell to cell.

Limitations and Warranty

enQuire Bio's FLI1 Anti-Human Monoclonal is available for Research Use Only. This antibody is guaranteed to work for a period of two years when properly stored.

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Anti-FLI1 Antibody Clone FLI1/1312

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