Immunohistochemical staining of Flk-1/KDR/VEGFR2  of human FFPE tissue followed by incubation with HRP labeled secondary and development with DAB substrate.

Flk-1/KDR/VEGFR2 [Polyclonal] Antibody (cGMP).

$ 158.00$ 868.00
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SKU: QIVD279
Species: Human
Tested Applications: IHC [IVD]
Available Conjugates:
Isotype: Rabbit Undetermined

Product NumberDescriptionPrice
QIVD279-0.1ml Size: 0.1 ml, Format: Concentrate $ 135.00
QIVD279-0.5ml Size: 0.5 ml, Format: Concentrate $ 465.00
QIVD279-1ml Size: 1 ml, Format: Concentrate $ 775.00
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Datasheets and Documentation
Product Datasheet
Certificate of Analysis and Tags (Coming Soon)
Lot Number:

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Reconsitution Instructions (Leave Blank if Liquid):

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SKU: QIVD279-0.1ml
Flk-1/KDR/VEGFR2 General Information
Alternate Names
Molecular Weight
151.5 kDa
Chromosomal Location
q12 [chr: 4] [chr_start: 55078259] [chr_end: 55125595] [strand: -1]
Curated Database and Bioinformatic Data
Gene SymbolKDR
Entrez Gene ID3791
RefSeq Protein Accession(s)NP_002244
RefSeq mRNA Accession(s)NM_002253;
RefSeq Genomic Accession(s)NG_012004; NC_000004
UniProt ID(s)P35968
PharmGKB ID(s)PA30086
KEGG Gene ID(s)hsa:3791
Associated Diseases (KEGG IDs)Hemangioma, capillary infantile (HCI) [MIM:602089]: A condition characterized by dull red, firm, dome-shaped hemangiomas, sharply demarcated from surrounding skin, usually presenting at birth or occurring within the first two or three months of life. They result from highly proliferative, localized growth of capillary endothelium and generally undergo regression and involution without scarring. {ECO:0000269|PubMed:11807987, ECO:0000269|PubMed:17344846, ECO:0000269|PubMed:18931684}. Disease susceptibility is associated with variations affecting the gene represented in this entry.; Plays a major role in tumor angiogenesis. In case of HIV-1 infection, the interaction with extracellular viral Tat protein seems to enhance angiogenesis in Kaposi's sarcoma lesions.
General Description of Flk-1/KDR/VEGFR2 .
This antibody reacts with a 180 kDa protein, known as Flk-1, KDR or vascular endothelial growth factor receptor 2 (VEGFR2). Flk-1 is a cell membrane receptor kinase. Flk-1 is a high affinity receptor for vascular endothelial growth factor and is putatively involved in the growth of endothelial cells and angiogenesis.

Antibody (Suitable for clinical applications)

Sample Type: FFPE Patient Samples.
Tested Applications: IHC. Approved for In Vitro Diagnostic Procedures on FFPE tissues. For tissue collection recommendations, please see datasheet sent with product.
Application Notes
Specification Recommendation
Recommended Dilution (Conc) 1:50-1:100
Pretreatment Citrate Buffer pH 6.0
Incubation Parameters 30 min at Room Temperature

Prior to use, inspect vial for the presence of any precipitate or other unusual physical properties. These can indicate that the antibody has degraded and is no longer suitable for patient samples. Please run positive and negative controls simultaneously with all patient samples to account and control for errors in laboratory procedure. Use of methods or materials not recommended by enQuire Bio including change to dilution range and detection system should be routinely validated by the user.

Clonality: Polyclonal
Anti-Flk-1/KDR/VEGFR2 Antibody Clone: Polyclonal
Host and Isotype: Rabbit Undetermined
Recommended Positive Control Sample: Angiosarcoma
Cellular Localization of Antibody Polyclonal Staining: Cytoplasmic
Buffer and Stabilizer: PBS with 1% BSA and 0.05% NaN3
Antibody Concentration: Lot specific. Plese contact tech support for data.
Immunogen: A synthetic peptide derived from the C-terminus of the precursor form of the mouse Flk-1.
Storage Conditions: This antibody should be stored refrigerated (2-8°C). This product should not be used past the expiration date printed on the vial.

Flk-1/KDR/VEGFR2 Information for Pathologists

Limitations and Warranty

This antibody is manufactured in accordance with clinical good manufacturing practices in an ISO13485:2016 certified production facility. It is intended for multiple uses including in vitro diagnostic use and research use only applications. Please see vial label for expiration date. We strive to always deliver antibodies with a shelf life of at least two years.

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Flk-1/KDR/VEGFR2 [Polyclonal] Antibody (cGMP).