Formalin-fixed, paraffin-embedded human Melanoma stained with gp1 / Melanosome Monoclonal Antibody (NKI-beteb),
Formalin-fixed, paraffin-embedded human Melanoma stained with gp1 / Melanosome Monoclonal Antibody (NKI-beteb),

Anti-gp100 / Melanosome / PMEL17 / SILV Antibody Clone NKI-beteb

$ 429.00
Please Select Product Options Below To View The Catalog Number.

SKU: 6490-MSM2
Species: Human, Horse, and Rat (-)
Tested Applications: Flow Cytometry, Immunofluorescence, Immunohistochemistry (IHC)
Available Conjugates: Unconjugated
Isotype: Mouse IgG2b kappa
Mass Spec Validated?: Not MS Validated

Product NumberDescriptionPrice
6490-MSM2-P1 Size: 100 ug, Tag: Unconjugated
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In Stock.
Flat Rate Shipping Anywhere in the US: $45
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SKU: 6490-MSM2-P1
gp100 / Melanosome / PMEL17 / SILV General Information
Alternate Names
Melanocyte protein PMEL, Premelanosome protein, PMEL, Silver locus protein homolog, SILV
Molecular Weight
90-100kDa
Chromosomal Location
12q13.2
Curated Database and Bioinformatic Data
Gene SymbolSILV
Entrez Gene ID6490
Ensemble Gene IDENSG00000185664
RefSeq Protein Accession(s)NP_001186982, XP_006719632, NP_001307050, NP_008859, XP_011536987, NP_001186983, NP_001307051
RefSeq mRNA Accession(s)XM_006719569, NM_001320122, NM_001200053, XM_011538685, NM_001320121, NM_006928 NM_001200054
RefSeq Genomic Accession(s)NC_000012, NC_018923, NG_028086
UniProt ID(s)P40967
UniGene ID(s)P40967
HGNC ID(s)10880
Cosmic ID(s)PMEL
KEGG Gene ID(s)hsa:6490
PharmGKB ID(s)PA35781
General Description of gp100 / Melanosome / PMEL17 / SILV.
By immunohistochemistry, it specifically recognizes a protein in melanocytes, melanomas. This MAb reacts with junctional, blue nevus cells, variably with fetal, neonatal melanocytes. Intradermal nevi, normal adult melanocytes,, non-melanocytic cells are negative. It does not stain tumor cells of epithelial, lymphoid, glial, or mesenchymal origin.This Mab labels formalin-fixed, paraffin-embedded melanomas, other tumors showing melanocytic differentiation.

Human, Horse, and Rat (-) Anti-gp100 / Melanosome / PMEL17 / SILV Antibody Product Attributes

Species: Human, Horse, and Rat (-)
Tested Applications: Flow Cytometry, Immunofluorescence, Immunohistochemistry (IHC).
Application Notes: Flow Cytometry (0.5-1ug of antibody/million cells in 0.1ml), Immunofluorescence (1-2ug of antibody/ml), Immunohistochemistry (IHC) (Formalin-fixed) (1-2ug of antibody/ml for 30 minutes at RT)
Clonality: Monoclonal
Anti-gp100 / Melanosome / PMEL17 / SILV Antibody Clone: NKI-beteb
Clone NKI-beteb Host and Isotype: Mouse IgG2b kappa
Anti-Human, Horse, and Rat (-) gp100 / Melanosome / PMEL17 / SILV Positive Control Sample: SK-MEL-28 cells or Melanoma
Cellular Localization of Antibody Cytoplasmic
Buffer and Stabilizer: 10mM PBS with 0.05% BSA & 0.05% azide.
Antibody Concentration: 200ug/ml
Antibody Purification Method:Protein A/G Purified
Immunogen: Membranes from a human melanoma metastasis
Storage Conditions: Store at 2 to 8° C (refrigerate). Stable for 24 months when properly stored.

gp100 / Melanosome / PMEL17 / SILV Previously Observed Antibody Staining Patterns

Limitations and Warranty

enQuire Bio's gp100 / Melanosome / PMEL17 / SILV Anti-Human, Horse Monoclonal is available for Research Use Only. This antibody is guaranteed to work for a period of two years when properly stored.

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Anti-gp100 / Melanosome / PMEL17 / SILV Antibody Clone NKI-beteb

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