Formalin-fixed, paraffin-embedded human Melanoma stained with gp1 Recombinant Rabbit Monoclonal Antibody (PMEL/1825R).
Formalin-fixed, paraffin-embedded human Melanoma stained with gp1 Recombinant Rabbit Monoclonal Antibody (PMEL/1825R).

Anti-gp100 / PMEL17 / SILV Antibody Clone PMEL/1825R

$ 228.00$ 618.00
Please Select Product Options Below To View The Catalog Number.

SKU: 6490-RBM5
Species: Human
Tested Applications: Immunohistochemistry (IHC)
Available Conjugates: Unconjugated
Isotype: Rabbit IgG kappa
Mass Spec Validated?: Not MS Validated

Product NumberDescriptionPrice
6490-RBM5-P0 Size: 20 ug, Tag: Unconjugated $ 228.00
6490-RBM5-P1 Size: 100 ug, Tag: Unconjugated $ 488.00
6490-RBM5-P2 Size: 200 ug, Tag: Unconjugated $ 618.00
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In Stock.
Flat Rate Shipping Anywhere in the US: $45
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SKU: 6490-RBM5-P0
gp100 / PMEL17 / SILV General Information
Alternate Names
Melanocyte protein PMEL, Premelanosome protein, PMEL, Silver locus protein homolog, SILV
Molecular Weight
90-100kDa
Chromosomal Location
12q13.2
Curated Database and Bioinformatic Data
Gene SymbolSILV
Entrez Gene ID6490
Ensemble Gene IDENSG00000185664
RefSeq Protein Accession(s)NP_001186982, XP_006719632, NP_001307050, NP_008859, XP_011536987, NP_001186983, NP_001307051
RefSeq mRNA Accession(s)XM_006719569, NM_001320122, NM_001200053, XM_011538685, NM_001320121, NM_006928 NM_001200054
RefSeq Genomic Accession(s)NC_000012, NC_018923, NG_028086
UniProt ID(s)P40967
UniGene ID(s)P40967
HGNC ID(s)10880
Cosmic ID(s)PMEL
KEGG Gene ID(s)hsa:6490
PharmGKB ID(s)PA35781
General Description of gp100 / PMEL17 / SILV.
Cytotoxic T lymphocytes (CTL s) recognize melanoma-associated antigens, which belong to three main groups. These groups include tumor-associated testis-specific antigens, melanocyte differentiation antigens and mutated or aberrantly expressed antigens, which are routinely used as markers to identify melanomas based on their binding to specific monoclonal antibodies. gp100, also designated ME20-M, ME20-S and PMEL 17, is classified as a melanocyte differentiation antigen and is expressed at low levels in normal cell lines and tissues, but is upregulated in melanocytes. gp100 is a highly glycosylated protein. It is also the product of proteolytic cleavage, which results in a secreted protein.

Human Anti-gp100 / PMEL17 / SILV Antibody Product Attributes

Species: Human
Tested Applications: Immunohistochemistry (IHC).
Clonality: Recombinant Monoclonal
Anti-gp100 / PMEL17 / SILV Antibody Clone: PMEL/1825R
Clone PMEL/1825R Host and Isotype: Rabbit IgG kappa
Anti-Human gp100 / PMEL17 / SILV Positive Control Sample: SK-MEL-28 cells or Melanoma
Cellular Localization of Antibody Cytoplasmic
Buffer and Stabilizer: 10mM PBS with or without 0.05% BSA & 0.05% azide.
Antibody Concentration: 200ug/ml
Antibody Purification Method:Protein A/G Purified
Immunogen: Recombinant full-length human SILV protein
Storage Conditions: Store at 2 to 8° C (refrigerate). Stable for 24 months when properly stored.

gp100 / PMEL17 / SILV Previously Observed Antibody Staining Patterns

Limitations and Warranty

enQuire Bio's gp100 / PMEL17 / SILV Recombinant Monoclonal is available for Research Use Only. This antibody is guaranteed to work for a period of two years when properly stored.

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Anti-gp100 / PMEL17 / SILV Antibody Clone PMEL/1825R

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