Formalin-fixed, paraffin-embedded human Placenta stained with hCG alpha Monoclonal Antibody (HCGa/53).
Formalin-fixed, paraffin-embedded human Placenta stained with hCG alpha Monoclonal Antibody (HCGa/53).

Anti-HCG-alpha Antibody Clone HCGa/53

$ 298.00
Please Select Product Options Below To View The Catalog Number.

SKU: 1081-MSM1
Species: Human
Tested Applications: Immunohistochemistry (IHC)
Available Conjugates: Unconjugated
Isotype: Mouse IgG1 kappa
Mass Spec Validated?: Not MS Validated

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Datasheets and Documentation
Product Datasheet
SKU: 1081-MSM1-P1
HCG-alpha General Information
Alternate Names
beta globin, haemoglobin beta, hemoglobin beta
Molecular Weight
~13kDa
Chromosomal Location
6q12-q21
Curated Database and Bioinformatic Data
Gene SymbolCGA
Entrez Gene ID1081
Ensemble Gene IDENSG00000135346
RefSeq Protein Accession(s)NP_001239312, NP_000726
RefSeq mRNA Accession(s)NM_001252383, NM_000735
RefSeq Genomic Accession(s)NC_000006, NC_018917
UniProt ID(s)P01215, Q6I9S8, A0A087WYZ4
UniGene ID(s)P01215, Q6I9S8, A0A087WYZ4
HGNC ID(s)1885
Cosmic ID(s)CGA
KEGG Gene ID(s)hsa:1081
PharmGKB ID(s)PA26433
General Description of HCG-alpha.
This MAb reacts with a protein of ~13kDa, identified as alpha sub-unit of HCG. HCG is a glycoprotein, which is secreted in large quantities by normal trophoblasts. It is present only in trace amounts in non-pregnant urine, sera but rises sharply during pregnancy. HCG is composed of two non-identical, non-covalently linked polypeptide chains designated as the ?, ? subunits. The ? subunit is identical to that of thyroid stimulating hormone (TSH), follicle stimulating hormone (FSH),, luteinizing hormone (LH).

Human Anti-HCG-alpha Antibody Product Attributes

Species: Human
Tested Applications: Immunohistochemistry (IHC).
Application Notes: Immunohistochemistry (IHC) (Formalin-fixed) (1-2ug of antibody/ml for 30 minutes at RT)
Clonality: Monoclonal
Anti-HCG-alpha Antibody Clone: HCGa/53
Clone HCGa/53 Host and Isotype: Mouse IgG1 kappa
Anti-Human HCG-alpha Positive Control Sample: JAR or TT Cells. Placenta
Cellular Localization of Antibody Cytoplasmic, secreted
Buffer and Stabilizer: 10mM PBS with 0.05% BSA & 0.05% azide.
Antibody Concentration: 200ug/ml
Antibody Purification Method:Protein A/G Purified
Immunogen: Recombinant hCG alpha protein
Storage Conditions: Store at 2 to 8° C (refrigerate). Stable for 24 months when properly stored.

HCG-alpha Previously Observed Antibody Staining Patterns

Observed Antibody Staining Data By Tissue Type:

Variations in HCG-alpha antibody staining intensity in immunohistochemistry on tissue sections are present across different anatomical locations. An intense signal was observed in cells in the anterior in pituitary gland and trophoblastic cells in the placenta. More moderate antibody staining intensity was present in cells in the anterior in pituitary gland and trophoblastic cells in the placenta. Low, but measureable presence of HCG-alpha could be seen in. We were unable to detect HCG-alpha in other tissues. Disease states, inflammation, and other physiological changes can have a substantial impact on antibody staining patterns. These measurements were all taken in tissues deemed normal or from patients without known disease.

Limitations and Warranty

enQuire Bio's HCG-alpha Anti-Human Monoclonal is available for Research Use Only. This antibody is guaranteed to work for a period of two years when properly stored.

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