Formalin-fixed, paraffin-embedded human Placenta stained with hCG beta Monoclonal Antibody (HCGb/54).
Formalin-fixed, paraffin-embedded human Placenta stained with hCG beta Monoclonal Antibody (HCGb/54).

Anti-HCG-beta Antibody Clone HCGb/54

$ 298.00
Please Select Product Options Below To View The Catalog Number.

SKU: 1082-MSM1
Species: Human
Tested Applications: Immunohistochemistry (IHC)
Available Conjugates: Unconjugated
Isotype: Mouse IgG1 kappa
Mass Spec Validated?: Not MS Validated

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Datasheets and Documentation
Product Datasheet
SKU: 1082-MSM1-P1
HCG-beta General Information
Alternate Names
Retinol binding protein 4, plasma RBP4
Molecular Weight
22kDa
Chromosomal Location
19q13.33
Curated Database and Bioinformatic Data
Gene SymbolCGB
Entrez Gene ID1082
Ensemble Gene IDENSG00000104827
RefSeq Protein Accession(s)NP_000728
RefSeq mRNA Accession(s)NM_000737
RefSeq Genomic Accession(s)NC_000019, NC_018930
UniProt ID(s)P01233, A0A0F7RQP8, Q3SY41, Q8WXL4, Q3KPI3, Q8WXL1, P0DN86, Q8WXL3, B9ZVP5, Q14000, Q8WXL2, Q13991, Q8WTT5, A1A5E0
UniGene ID(s)P01233, A0A0F7RQP8, Q3SY41, Q8WXL4, Q3KPI3, Q8WXL1, P0DN86, Q8WXL3, B9ZVP5, Q14000, Q8WXL2, Q13991, Q8WTT5, A1A5E0
HGNC ID(s)1886
Cosmic ID(s)CGB3
KEGG Gene ID(s)hsa:1082
General Description of HCG-beta.
This MAb reacts with a protein of 22kDa, identified as beta sub-unit of HCG. It does not cross react with the alpha sub-unit. HCG is a glycoprotein, which is secreted in large quantities by normal trophoblasts. It is present only in trace amounts in non-pregnant urine, sera but rises sharply during pregnancy. HCG is composed of two non-identical, non-covalently linked polypeptide chains designated as the alpha, beta subunits. The beta subunit is identical to that of thyroid stimulating hormone (TSH), follicle stimulating hormone (FSH),, luteinizing hormone (LH). hCG MAb detects cells, tumors of trophoblastic origin such as choriocarcinoma. Large cell carcinoma, adenocarcinoma of the lung demonstrate anti-hCG positivity in 90%, 60% of cases respectively. 20% of lung squamous cell carcinomas are positive. hCG expression by non-trophoblastic tumors may indicate aggressive behavior.

Human Anti-HCG-beta Antibody Product Attributes

Species: Human
Tested Applications: Immunohistochemistry (IHC).
Application Notes: Immunohistochemistry (IHC) (Formalin-fixed) (0.5-1ug of antibody/ml, 30 min RT)
Clonality: Monoclonal
Anti-HCG-beta Antibody Clone: HCGb/54
Clone HCGb/54 Host and Isotype: Mouse IgG1 kappa
Anti-Human HCG-beta Positive Control Sample: JAR or TT Cells. Placenta
Cellular Localization of Antibody Cytoplasmic, secreted
Buffer and Stabilizer: 10mM PBS with 0.05% BSA & 0.05% azide.
Antibody Concentration: 200ug/ml
Antibody Purification Method:Protein A/G Purified
Immunogen: Recombinant hCG beta protein
Storage Conditions: Store at 2 to 8° C (refrigerate). Stable for 24 months when properly stored.

HCG-beta Previously Observed Antibody Staining Patterns

Limitations and Warranty

enQuire Bio's HCG-beta Anti-Human Monoclonal is available for Research Use Only. This antibody is guaranteed to work for a period of two years when properly stored.

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