Formalin-fixed, paraffin-embedded human Tonsil stained with HLA-DP/-DQ/-DR Monoclonal Antibody (CR3/43).
Formalin-fixed, paraffin-embedded human Tonsil stained with HLA-DP/-DQ/-DR Monoclonal Antibody (CR3/43).

Anti-HLA-DP/-DQ/-DR Antibody Clone CR3/43

$ 118.00$ 418.00
Please Select Product Options Below To View The Catalog Number.

SKU: 3115-MSM3
Species: Human
Tested Applications: Immunohistochemistry (IHC)
Available Conjugates: Unconjugated
Isotype: Mouse IgG1
Mass Spec Validated?: Not MS Validated

Product NumberDescriptionPrice
3115-MSM3-P0 Size: 20 ug, Tag: Unconjugated $ 118.00
3115-MSM3-P1 Size: 100 ug, Tag: Unconjugated $ 298.00
3115-MSM3-P2 Size: 200 ug, Tag: Unconjugated $ 418.00
Shipping Information
In Stock: 1-2 Day Lead Time.
Flat Rate Shipping Anywhere in the US: $45
Datasheets and Documentation
Product Datasheet
SKU: 3115-MSM3-P0
HLA-DP/-DQ/-DR General Information
Alternate Names
HLA-DPB1, HLA-DQA1, HLA-DQB1, HLA-DRA, HLA-DRB1, HLA-DRB3, HLA-DRB4, HLA-DRB5,, anti-HLA-DPB1 antibody, anti-HLA-DQA1 antibody, anti-HLA-DQB1 antibody, anti-HLA-DRA antibody, anti-HLA-DRB1 antibody, anti-HLA-DRB3 antibody, anti-HLA-DRB4 antibody, anti-HLA-DRB5, antibody
Molecular Weight
36kDa (? chain) and 27kDa (? chain)
Chromosomal Location
6p21.3 (HLA-DP ;HLA-DR)
Curated Database and Bioinformatic Data
Gene SymbolHLA-DP ;HLA-DQ ;HLA-DR
Entrez Gene ID3115
Ensemble Gene IDENSG00000226826, ENSG00000229295, ENSG00000230763, ENSG00000237710, ENSG00000230708, ENSG00000236693, ENSG00000215048, ENSG00000223865
RefSeq Protein Accession(s)NP_002112
RefSeq mRNA Accession(s)NM_002121
RefSeq Genomic Accession(s)NG_167245, NG_033242, NG_167247, NC_018917, NG_113891, NG_167246, NG_167249, NC_000006, NG_167244, NG_167248
UniProt ID(s)I4EC15, P04440
UniGene ID(s)I4EC15, P04440
HGNC ID(s)4940
Cosmic ID(s)HLA-DPB1
KEGG Gene ID(s)hsa:3115
PharmGKB ID(s)PA35064
General Description of HLA-DP/-DQ/-DR.
Reacts with a common epitope of human major histocompatibility (MHC) class II antigens, HLA-DP, -DQ and -DR. Human MHC class II antigens are transmembrane glycoproteins composed of an ? chain (36kDa) and a ? chain (27kDa). They are expressed primarily on antigen presenting cells such as B lymphocytes, monocytes, macrophages, and thymic epithelial cells and are also present on activated T lymphocytes. Human MHC class II genes are located in the HLA-D region that encodes at least six ? and ten ? chain genes. Three loci, DR, DQ and DP, encode the major expressed products of the human class II region. The human MHC class II molecules bind intracellularly processed peptides and present them to T-helper cells. They, therefore, have a critical role in the initiation of the immune response. It has been shown that some autoimmune diseases are associated with certain class II alleles.

Human Anti-HLA-DP/-DQ/-DR Antibody Product Attributes

Species: Human
Tested Applications: Immunohistochemistry (IHC).
Clonality: Monoclonal
Anti-HLA-DP/-DQ/-DR Antibody Clone: CR3/43
Clone CR3/43 Host and Isotype: Mouse IgG1
Anti-Human HLA-DP/-DQ/-DR Positive Control Sample: Raji cells. Tonsil or lymph node
Cellular Localization of Antibody Cell surface
Buffer and Stabilizer: 10mM PBS with 0.05% BSA and 0.05% Azide
Antibody Concentration: 200 ug/ml
Antibody Purification Method:Protein A/G Purified
Immunogen: Cells from human tonsil
Storage Conditions: Store at 2 to 8° C (refrigerate). Stable for 24 months when properly stored.

HLA-DP/-DQ/-DR Previously Observed Antibody Staining Patterns

Observed Subcellular, Organelle Specific Staining Data:

Anti-HLA-DPB1 antibody staining is expected to be primarily localized to the cell junctions and nucleus.

Limitations and Warranty

enQuire Bio's HLA-DP/-DQ/-DR Anti-Human Monoclonal is available for Research Use Only. This antibody is guaranteed to work for a period of two years when properly stored.

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Anti-HLA-DP/-DQ/-DR Antibody Clone CR3/43

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