Formalin-fixed, paraffin-embedded human Tonsil stained with HLA-DP/DR Monoclonal Antibody (Bra-14).

Anti-HLA-DP / HLA-DR Antibody Clone Bra-14

$ 298.00
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SKU: 3115-MSM2
Species: Human
Tested Applications: Flow Cytometry, Immunofluorescence, Immunohistochemistry (IHC)
Available Conjugates: Unconjugated
Isotype: Mouse IgG3 kappa
Mass Spec Validated?: Not MS Validated

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Datasheets and Documentation
Product Datasheet
SKU: 3115-MSM2-P1
HLA-DP / HLA-DR General Information
Alternate Names
HLA-DP: HLA class II histocompatibility antigen DP alpha 1 chain, HLA DP1A, HLA SB alpha chain, HLADP, HLADPA1, HLASB, HLASB histocompatibility type, Human MHC class II HLA SB alpha, Major histocompatibility complex class II DP alpha 1, MHC class II DP3 alpha, MHC class II DPA1, PLT1, Primed lymphocyte test 1 HLA-DR: DR alpha chain, HLA class II histocompatibility antigen, HLA class II histocompatibility antigen DR alpha chain, HLA DRA, HLA DRA1, HLA-DRA, HLADRA1, Major histocompatibility complex class II DR alpha, MHC cell surface glycoprotein, MHC class II antigen DRA, anti-HLA-DP: HLA class II histocompatibility antigen DP alpha 1 chain antibody, anti-HLA DP1A antibody, anti-HLA SB alpha chain antibody, anti-HLADP antibody, anti-HLADPA1 antibody, anti-HLASB antibody, anti-HLASB histocompatibility type antibody, anti-Human MHC class II HLA SB alpha antibody, anti-Major histocompatibility complex class II DP alpha 1 antibody, anti-MHC class II DP3 alpha antibody, anti-MHC class II DPA1 antibody, anti-PLT1 antibody, anti-Primed lymphocyte test 1 HLA-DR: DR alpha chain antibody, anti-HLA class II histocompatibility antigen antibody, anti-HLA class II histocompatibility antigen DR alpha chain antibody, anti-HLA DRA antibody, anti-HLA DRA1 antibody, anti-HLA-DRA antibody, anti-HLADRA1 antibody, anti-Major histocompatibility complex class II DR alpha antibody, anti-MHC cell surface glycoprotein antibody, anti-MHC class II antigen DRA antibody
Molecular Weight
36kDa (? chain), 27kDa (? chain)
Chromosomal Location
6p21.3 (HLA-DP & HLA-DR)
Curated Database and Bioinformatic Data
Gene SymbolHLA-DPB1 & HLA-DRA
Entrez Gene ID3115, 3122
Ensemble Gene IDENSG00000226826, ENSG00000229295, ENSG00000230763, ENSG00000237710, ENSG00000230708, ENSG00000236693, ENSG00000215048, ENSG00000223865, ENSG00000227993, ENSG00000204287, ENSG00000277263, ENSG00000230726, ENSG00000234794, ENSG00000228987, ENSG00000226260, ENSG00000206308
RefSeq Protein Accession(s)NP_002112, NP_061984
RefSeq mRNA Accession(s)NM_002121, NM_019111
RefSeq Genomic Accession(s)NG_167245, NG_033242, NG_167247, NC_018917, NG_113891, NG_167246, NG_167249, NC_000006, NG_167244, NG_167248NC_000006, NG_187692, NG_167247, NG_113891, NC_018917, NG_167245, NG_167246, NG_167249, NG_002392, NG_167248
UniProt ID(s)I4EC15, P04440, P01903, A0A0G2JMH6
UniGene ID(s)I4EC15, P04440, P01903, A0A0G2JMH6
HGNC ID(s)4940, 4947
Cosmic ID(s)HLA-DPB1, HLA-DRA
KEGG Gene ID(s)hsa:3115, hsa:3122
PharmGKB ID(s)PA35064, PA35071
General Description of HLA-DP / HLA-DR.
Reacts with a common epitope of human major histocompatibility (MHC) class II antigens, HLA-DR, DP. Human MHC class II antigens are transmembrane glycoproteins composed of an chain (36kDa), a chain (27kDa). They are expressed primarily on antigen presenting cells such as B lymphocytes, monocytes, macrophages,, thymic epithelial cells, are also present on activated T lymphocytes. Human MHC class II genes are located in the HLA-D region that encodes at least six , ten chain genes. Three loci, DR, DQ, DP, encode the major expressed products of the human class II region. The human MHC class II molecules bind intracellularly processed peptides, present them to T-helper cells. They, therefore, have a critical role in the initiation of the immune response. It has been shown that some autoimmune diseases are associated with certain class II alleles.

Human Anti-HLA-DP / HLA-DR Antibody Product Attributes

Species: Human
Tested Applications: Flow Cytometry, Immunofluorescence, Immunohistochemistry (IHC).
Application Notes: Flow Cytometry (0.5-1ug of antibody/million cells in 0.1ml), Immunofluorescence (0.5-1ug of antibody/ml), Immunohistochemistry (IHC) (Formalin-fixed) (0.5-1ug of antibody/ml for 30 minutes at RT)
Clonality: Monoclonal
Anti-HLA-DP / HLA-DR Antibody Clone: Bra-14
Clone Bra-14 Host and Isotype: Mouse IgG3 kappa
Anti-Human HLA-DP / HLA-DR Positive Control Sample: Raji cells. Tonsil or lymph node
Cellular Localization of Antibody Cell surface
Buffer and Stabilizer: 10mM PBS with 0.05% BSA & 0.05% azide.
Antibody Concentration: 200ug/ml
Antibody Purification Method:Protein A/G Purified
Immunogen: Human REH cells
Storage Conditions: Store at 2 to 8° C (refrigerate). Stable for 24 months when properly stored.

HLA-DP / HLA-DR Previously Observed Antibody Staining Patterns

Limitations and Warranty

enQuire Bio's HLA-DP / HLA-DR Anti-Human Monoclonal is available for Research Use Only. This antibody is guaranteed to work for a period of two years when properly stored.

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Anti-HLA-DP / HLA-DR Antibody Clone Bra-14