Formalin-fixed, paraffin-embedded human Placenta stained with hCG Monoclonal Antibody (HCGab/52).

Human Anti-Human Chorionic Gonadotropin Antibody Clone HCGab/52

$ 329.00
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SKU: MSM1-52
Species: Human
Tested Applications: Immunohistochemistry (IHC)
Available Conjugates: Unconjugated
Isotype: Mouse IgG1 kappa
Mass Spec Validated?: Not MS Validated

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Datasheets and Documentation
Product Datasheet
SKU: MSM1-52-P1
Human Chorionic Gonadotropin General Information
Alternate Names
Chorionic Gonadotropin, hCG
Molecular Weight
~35kDa (intact hCG)
Chromosomal Location
6q12-q21 (HCG-alpha) & 19q13.33 (HCG-beta)
Curated Database and Bioinformatic Data
Gene SymbolCGA (HCG-alpha) & CGB (HCG-beta)
Entrez Gene ID1081, 1082
Ensemble Gene IDENSG00000135346, ENSG00000104827
RefSeq Protein Accession(s)NP_001239312, NP_000726, NP_000728
RefSeq mRNA Accession(s)NM_001252383, NM_000735NM_000737
RefSeq Genomic Accession(s)NC_000006, NC_018917NC_000019, NC_018930
UniProt ID(s)P01215, Q6I9S8, A0A087WYZ4, P01233, A0A0F7RQP8, Q3SY41, Q8WXL4, Q3KPI3, Q8WXL1, P0DN86, Q8WXL3, B9ZVP5, Q14000, Q8WXL2, Q13991, Q8WTT5, A1A5E0
UniGene ID(s)P01215, Q6I9S8, A0A087WYZ4, P01233, A0A0F7RQP8, Q3SY41, Q8WXL4, Q3KPI3, Q8WXL1, P0DN86, Q8WXL3, B9ZVP5, Q14000, Q8WXL2, Q13991, Q8WTT5, A1A5E0
HGNC ID(s)1885, 1886
Cosmic ID(s)CGA, CGB3
KEGG Gene ID(s)hsa:1081, hsa:1082
PharmGKB ID(s)PA26433
General Description of Human Chorionic Gonadotropin.
This MAb is a very special because it reacts ONLY with the intact-HCG, not with either free alpha- or free beta-chain of HCG. HCG is a glycoprotein, is composed of two non-identical, non-covalently linked polypeptide chains designated as the ? , ? subunits. The ? subunit is identical to that of thyroid stimulating hormone (TSH), follicle stimulating hormone (FSH),, luteinizing hormone (LH). HCG is secreted in large quantities by normal trophoblasts. It is present only in trace amounts in non-pregnant urine, sera but rises sharply during pregnancy. HCG MAb detects cells, tumors of trophoblastic origin such as choriocarcinoma. Large cell carcinoma, adenocarcinoma of the lung demonstrate anti-hCG positivity in 90%, 60% of cases respectively. 20% of lung squamous cell carcinomas are positive. HCG expression by non-trophoblastic tumors may indicate aggressive behavior.

Human Anti-Human Chorionic Gonadotropin Antibody Product Attributes

Species: Human
Tested Applications: Immunohistochemistry (IHC).
Application Notes: Immunohistochemistry (IHC) (Formalin-fixed) (0.5-1ug of antibody/ml for 30 minutes at RT)
Clonality: Monoclonal
Anti-Human Chorionic Gonadotropin Antibody Clone: HCGab/52
Clone HCGab/52 Host and Isotype: Mouse IgG1 kappa
Anti-Human Human Chorionic Gonadotropin Positive Control Sample: JAR or TT Cells. Placenta
Cellular Localization of Antibody Cytoplasmic, Secreted
Buffer and Stabilizer: 10mM PBS with 0.05% BSA & 0.05% azide.
Antibody Concentration: 200ug/ml
Antibody Purification Method:Protein A/G Purified
Immunogen: Purified hCG protein
Storage Conditions: Store at 2 to 8° C (refrigerate). Stable for 24 months when properly stored.

Human Chorionic Gonadotropin Previously Observed Antibody Staining Patterns

Limitations and Warranty

enQuire Bio's Human Chorionic Gonadotropin Anti-Human Monoclonal is available for Research Use Only. This antibody is guaranteed to work for a period of two years when properly stored.

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