Formalin-fixed, paraffin-embedded human Tonsil stained with IgM Monoclonal Antibody (SPM188)

Anti-IgM Antibody Clone SPM188

Name: Anti-IgM Antibody Clone SPM188
Brand: enQuire Bio
Price: 429 USD
Availability: InStock

$ 488.00

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SKU: 3507-MSM1X
Species: Human
Tested Applications: Flow Cytometry, Immunofluorescence, Immunohistochemistry (IHC)
Available Conjugates: Unconjugated
Isotype: Mouse IgG1 kappa
Mass Spec Validated?: Not MS Validated

Product Number	Description	Price
3507-MSM1X-P1	Size: 100 ug, Tag: Unconjugated

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In Stock.

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Datasheets and Documentation

Product Datasheet

Certificate of Analysis and Tags (Coming Soon)

SKU: 3507-MSM1X-P1

IgM General Information
Alternate Names
Ig mu chain C region, IGHM
Molecular Weight
50-75kDa
Chromosomal Location
14q32.33
Curated Database and Bioinformatic Data
Gene Symbol	IGHM
Entrez Gene ID	3507
RefSeq Genomic Accession(s)	NC_000014, NG_187600, NC_018925, NG_001019
UniGene ID(s)
HGNC ID(s)	5541
Cosmic ID(s)	IGHM
General Description of IgM.
Recognizes a protein of 75kDa, identified as mu heavy chain of human immunoglobulins. It does not cross-react with alpha (IgA), gamma (IgG), epsilon (IgE), or delta (IgD), heavy chains, T-cells, monocytes, granulocytes, or erythrocytes. Monomeric IgM is expressed as a membrane bound antibody on the surface of B cells, as a pentamer when secreted by plasma cells. IgM antibody is prominent in early immune responses to most antigens. Aberrant levels are associated with immune deficiency states, hereditary deficiencies, myeloma, Waldenstrom's macroglobulinemia, chronic infection, hepatocellular disease. This MAb is useful in the identification of leukemias, plasmacytomas,, certain non-Hodgkin s lymphomas. The most common feature of these malignancies is the restricted expression of a single heavy chain class. Demonstration of clonality in lymphoid infiltrates indicates that the infiltrate is clonal, therefore malignant.

Human Anti-IgM Antibody Product Attributes

Species: Human

Tested Applications: Flow Cytometry, Immunofluorescence, Immunohistochemistry (IHC).

Application Notes: Flow Cytometry (0.5-1ug of antibody/million cells in 0.1ml), Immunofluorescence (0.5-1ug of antibody/ml), Immunohistochemistry (IHC) (Formalin-fixed) (0.5-1ug of antibody/ml for 30 minutes at RT)

Clonality: Monoclonal

Anti-IgM Antibody Clone: SPM188

Clone SPM188 Host and Isotype: Mouse IgG1 kappa

Anti-Human IgM Positive Control Sample: 293T, Raji or hPBL cells. Tonsil or Spleen.

Cellular Localization of Antibody Cytoplasm, Cell Surface, Secreted

Buffer and Stabilizer: 10mM PBS with 0.05% BSA & 0.05% azide.

Antibody Concentration: 200ug/ml

Antibody Purification Method:Protein A/G Purified

Immunogen: Heavy chain of human IgM

Storage Conditions: Store at 2 to 8Â° C (refrigerate). Stable for 24 months when properly stored.

IgM Previously Observed Antibody Staining Patterns

Limitations and Warranty

enQuire Bio's IgM Anti-Human Monoclonal is available for Research Use Only. This antibody is guaranteed to work for a period of two years when properly stored.

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