Mouse lymphoid cells were stimulated in the presence of a protein transport inhibitor. Cells were then fixed, permeabilized, stained with APC Mouse Anti-CD4 and intracellularly with 0.125 ug PE Mouse Anti-IL-4 (QAB81) (right panel) or 0.125 ug PE Rat Ig

Anti-IL-4 Antibody [11B11]

$ 68.00$ 238.00
Please Select Product Options Below To View The Catalog Number.

Species: Mouse
Tested Applications: Flow Cytometry
Available Conjugates: APC ;Unconjugated ;PE
Isotype: Rat IgG1 kappa
Mass Spec Validated?: Not MS Validated

Tag Clear selection
Shipping Information
In Stock: 1-2 Day Lead Time.
Flat Rate Shipping Anywhere in the US: $45
Datasheets and Documentation
Product Datasheet
SKU: QAB81-APC-25ug
IL-4 / Interleukin-4 General Information
Alternate Names
IL4, Interleukin-4, BSF-1, BSF1, IL-4, BCGF1, BCGF-1
Curated Database and Bioinformatic Data
Gene SymbolIl4
Entrez Gene ID16189
Ensemble Gene IDENSMUSG00000000869
RefSeq Protein Accession(s)NP_067258
RefSeq mRNA Accession(s)NM_021283, NR_027491
RefSeq Genomic Accession(s)NC_000077
UniProt ID(s)P07750
UniGene ID(s)P07750
Cosmic ID(s)Il4
KEGG Gene ID(s)mmu:16189
General Description of IL-4 / Interleukin-4.
The 11B11 antibody binds to mouse Interleukin-4 (IL-4), a 14 kDa cytokine that is largely secreted by activated T cells of the Th2 subset, and to some degree by NKT and mast cells. This cytokine acts as a stimulatory factor for B cells, inducing their proliferation and differentiation, as well as playing a role in immunoglobulin class-switching. IL-4 may also provide autocrine stimulation for T cells, and affect the function of antigen presenting cells such as macrophages and dendritic cells. IL-4 can bind and signal via three cell surface receptor types: CD124 by itself, CD124 in combination with the common gamma chain (type I complex), or CD124 combined with CD213a1 (type II complex).The 11B11 antibody is widely used for detection of intracellular levels of IL-4 protein by flow cytometry, as well as for analysis of soluble cytokine as measured by ELISA, and in functional assays to neutralization cytokine-receptor interactions. Please choose the appropriate format for each application.

Mouse Anti-IL-4 / Interleukin-4 Antibody Product Attributes

Species: Mouse
Tested Applications: Flow Cytometry.
Application Notes: See Product Datasheet for Recommended Dilution Range. Requires Experimental Optimization
Clonality: Monoclonal Antibody
Anti-IL-4 / Interleukin-4 Antibody Clone: 11B11
Clone 11B11 Host and Isotype: Rat IgG1 kappa
Buffer and Stabilizer: 10 mM NaH2PO4, 150 mM NaCl, 0.09% NaN3, 0.1% gelatin, pH7.2
Antibody Concentration: 0.2 mg/mL
Storage Conditions: 2-8C protected from light. Stable for 12 Months. Do Not Freeze.

IL-4 / Interleukin-4 Previously Observed Antibody Staining Patterns

Selected References

Cook PC, Jones LH, Jenkins SJ, Wynn TA, Allen JE, and MacDonald AS. 2012. Proc. Natl. Acad. Sci. 109: 9977-9982. (in vivo blocking)Altin JA, Goodnow CC, and Cook MC. 2012. J. Immunol. 5478-5488. (Flow cytometry)Tofukuji S, Kuwahara M, Suzuki J, Ohara O, Nakayama T, and Yamashita M. 2012. J. Immunol. 188: 4846-4857. (in vitro Th1 polarization)Weber KS, Hildner K, Murphy KM and Allen PM. 2010 J. Immunol. 185: 2836-2846 (in vitro Th1 polarization, ELISA)Odobasic D, Kitching AR, Semple TJ, Timoshanko JR, Tipping PG, and Holdsworth SR. 2005. J. Am. Soc. Nephrol. 16: 2012-2022. (in vivo activation, Immunofluorescence microscopy - frozen tissue, Immunohistochemistry - frozen tissue)

Limitations and Warranty

enQuire Bio's Mouse Anti-IL-4 Monoclonal is available for Research Use Only. This antibody is guaranteed to work for a period of two years when properly stored.

There are no reviews yet.

Be the first to review “Anti-IL-4 Antibody [11B11]”

Your email address will not be published. Required fields are marked *

Share a Protocol (View Reviewed Protocols Below)

Protocol Title




  protocol submission gif

enQuire Bio, LLC   1825 Lawrence St, Ste 115   Denver, CO 80202
Phone: 1-855-344-1400 | enquire@enquirebio.com | Fax: 1-720-897-3730
Customer Service Available M-F 8AM-6PM MST or 24/7 Via Email
Scroll to top

We consume cookies ensure that we give you the best experience on our website. If you continue to use this site we will assume that you are happy with it. Dismiss

Anti-IL-4 Antibody [11B11]https://enquirebio.com/wp-content/uploads/2017/10/enQuire-Bio-QAB81-APC-100ug-anti-IL-4-Interleukin-4-antibody-10-300x140.pnghttps://enquirebio.com/wp-content/uploads/2017/10/enQuire-Bio-QAB81-PE-100ug-anti-IL-4-Interleukin-4-antibody-10-300x138.png