Formalin-fixed, paraffin-embedded Rat Pancreas stained with Insulin Monoclonal Antibody (IRDN/794).
Formalin-fixed, paraffin-embedded Rat Pancreas stained with Insulin Monoclonal Antibody (IRDN/794).

Anti-Insulin / IRDN Antibody Clone IRDN/794

$ 298.00
Please Select Product Options Below To View The Catalog Number.

SKU: 3630-MSM4
Species: Human, Cow Pig, Mouse, and Rat
Tested Applications: Flow Cytometry, Immunofluorescence, Immunohistochemistry (IHC)
Available Conjugates: Unconjugated
Isotype: Mouse IgG1 kappa
Mass Spec Validated?: Not MS Validated

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Datasheets and Documentation
Product Datasheet
SKU: 3630-MSM4-P1
Insulin / IRDN General Information
Alternate Names
INS, Insulin
Molecular Weight
6kDa
Chromosomal Location
11p15.5
Curated Database and Bioinformatic Data
Gene SymbolINS
Entrez Gene ID3630
Ensemble Gene IDENSG00000254647
RefSeq Protein Accession(s)NP_001278826, NP_001172026, NP_000198, NP_001172027
RefSeq mRNA Accession(s)NM_001291897, NM_001185097, NM_000207, NM_001185098
RefSeq Genomic Accession(s)NC_018922, NG_007114, NC_000011, NG_050578
UniProt ID(s)I3WAC9, P01308
UniGene ID(s)I3WAC9, P01308
HGNC ID(s)6081
Cosmic ID(s)INS
KEGG Gene ID(s)hsa:3630
PharmGKB ID(s)PA201
General Description of Insulin / IRDN.
Recognizes a polypeptide which is identified as insulin, a 51-amino acid polypeptide composed of A, B chains connected through the C-peptide. Proinsulin, which has very little biological activity, is cleaved by proteases within its cell of origin into the insulin molecule, the C-terminal basic residue. Insulin enhances membrane transport of glucose, amino acids,, certain ions. It also promotes glycogen storage, formation of triglycerides,, synthesis of proteins, nucleic acids. Deficiency of insulin results in diabetes mellitus. The main storage site for insulin is the pancreatic islets. Antibodies to insulin are important as beta-cell, insulinoma marker.

Human, Cow Pig, Mouse, and Rat Anti-Insulin / IRDN Antibody Product Attributes

Species: Human, Cow Pig, Mouse, and Rat
Tested Applications: Flow Cytometry, Immunofluorescence, Immunohistochemistry (IHC).
Application Notes: Flow Cytometry (0.5-1ug of antibody/million cells in 0.1ml), Immunofluorescence (1-2ug of antibody/ml), Immunohistochemistry (IHC) (Formalin-fixed) (0.1-0.2ug of antibody/ml for 30 minutes at RT)
Clonality: Monoclonal
Anti-Insulin / IRDN Antibody Clone: IRDN/794
Clone IRDN/794 Host and Isotype: Mouse IgG1 kappa
Anti-Human, Cow Pig, Mouse, and Rat Insulin / IRDN Positive Control Sample: MIA PaCa-2 cells or Pancreas
Cellular Localization of Antibody Cytoplasmic
Buffer and Stabilizer: 10mM PBS with 0.05% BSA & 0.05% azide.
Antibody Concentration: 200ug/ml
Antibody Purification Method:Protein A/G Purified
Immunogen: Recombinant INS protein
Storage Conditions: Store at 2 to 8° C (refrigerate). Stable for 24 months when properly stored.

Insulin / IRDN Previously Observed Antibody Staining Patterns

Limitations and Warranty

enQuire Bio's Insulin / IRDN Anti-Human Monoclonal is available for Research Use Only. This antibody is guaranteed to work for a period of two years when properly stored.

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