Human Anti-Interferon gamma Antibody Product Attributes
Tested Applications: Immunohistochemistry (IHC).
Anti-Interferon gamma Antibody Clone: IFNG/466
Clone IFNG/466 Host and Isotype: Mouse IgG2b kappa
Anti-Human Interferon gamma Positive Control Sample: PMA stimulated human peripheral blood mononuclear cells. Renal or testicular carcinoma.
Cellular Localization of Antibody
Cytoplasmic ;Cell Surface
Buffer and Stabilizer: 10mM PBS with 0.05% BSA and 0.05% Azide
Antibody Concentration: 200 ug/ml
Antibody Purification Method:Protein A/G Purified
Immunogen: Purified recombinant human IFN-gamma
Storage Conditions: Store at 2 to 8Â° C (refrigerate). Stable for 24 months when properly stored.
Interferon gamma Previously Observed Antibody Staining Patterns
Observed Antibody Staining Data By Tissue Type:Variations in Interferon gamma antibody staining intensity in immunohistochemistry on tissue sections are present across different anatomical locations. Low, but measureable presence of Interferon gamma could be seen inadipocytes in mesenchymal tissue, cells in the endometrial stroma in endometrium, cells in the glomeruli in kidney, cells in the tubules in kidney, fibroblasts in skin, glandular cells in the adrenal gland, appendix, cervix, uterine, duodenum, epididymis, gallbladder, parathyroid gland, rectum, seminal vesicle, small intestine and stomach, keratinocytes in skin, Langerhans in skin, Leydig cells in the testis, macrophages in lung, melanocytes in skin, myocytes in heart muscle and skeletal muscle, neuronal cells in the hippocampus, non-germinal center cells in the tonsil, pneumocytes in lung, respiratory epithelial cells in the nasopharynx, smooth muscle cells in the smooth muscle, squamous epithelial cells in the oral mucosa and urothelial cells in the urinary bladder. We were unable to detect Interferon gamma in other tissues. Disease states, inflammation, and other physiological changes can have a substantial impact on antibody staining patterns. These measurements were all taken in tissues deemed normal or from patients without known disease.
Observed Antibody Staining Data By Tissue Disease Status:Tissues from cancer patients, for instance, have their own distinct pattern of Interferon gamma expression as measured by anti-Interferon gamma antibody immunohistochemical staining. The average level of expression by tumor is summarized in the table below. The variability row represents patient to patient variability in IHC staining.
|Sample Type||breast cancer||carcinoid||cervical cancer||colorectal cancer||endometrial cancer||glioma||head and neck cancer||liver cancer||lung cancer||lymphoma||melanoma||ovarian cancer||pancreatic cancer||prostate cancer||renal cancer||skin cancer||stomach cancer||testicular cancer||thyroid cancer||urothelial cancer|
Limitations and Warranty
enQuire Bio's Interferon gamma Anti-Human Monoclonal is available for Research Use Only. This antibody is guaranteed to work for a period of two years when properly stored.
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