Formalin-fixed, paraffin-embedded human Tonsil stained with Kappa Light Chain Monoclonal Antibody (SPM58).
Formalin-fixed, paraffin-embedded human Tonsil stained with Kappa Light Chain Monoclonal Antibody (SPM58).

Anti-Kappa Light Chain Antibody Clone SPM508

$ 298.00
Please Select Product Options Below To View The Catalog Number.

SKU: 3514-MSM1X
Species: Human and Rat (-)
Tested Applications: Flow Cytometry, Immunofluorescence, Western Blot, Immunohistochemistry (IHC)
Available Conjugates: Unconjugated
Isotype: Mouse IgG1 kappa
Mass Spec Validated?: Not MS Validated

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In Stock: 1-2 Day Lead Time.
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Datasheets and Documentation
Product Datasheet
SKU: 3514-MSM1X-P1
Kappa Light Chain General Information
Alternate Names
Immunoglobulin kappa constant, IGKC
Molecular Weight
~22.5kDa
Chromosomal Location
2p11.2
Curated Database and Bioinformatic Data
Gene SymbolIGKC
Entrez Gene ID3514
RefSeq Genomic Accession(s)NC_000002, NG_000834, NC_018913
UniGene ID(s)
HGNC ID(s)5716
Cosmic ID(s)IGKC
General Description of Kappa Light Chain.
This MAb is specific to kappa light chain of immunoglobulin, shows no cross-reaction with lambda light chain or any of the five heavy chains. In mammals, the two light chains in an antibody are always identical, with only one type of light chain, kappa or lambda. The ratio of kappa to lambda is 70:30. However, with the occurrence of multiple myeloma or other B-cell malignancies this ratio is disturbed. Antibody to the kappa light chain is reportedly useful in the identification of leukemias, plasmacytomas,, certain non-Hodgkin's lymphomas. Demonstration of clonality in lymphoid infiltrates indicates that the infiltrate is malignant.

Human and Rat (-) Anti-Kappa Light Chain Antibody Product Attributes

Species: Human and Rat (-)
Tested Applications: Flow Cytometry, Immunofluorescence, Western Blot, Immunohistochemistry (IHC).
Application Notes: Flow Cytometry (0.5-2.0ug of antibody/million cells in 0.1ml), Immunofluorescence (0.5-1ug of antibody/ml), Western Blot (0.5-1ug of antibody/ml), Immunohistochemistry (IHC) (Formalin-fixed) (0.5-1ug of antibody/ml for 30 min at RT)
Clonality: Monoclonal
Anti-Kappa Light Chain Antibody Clone: SPM508
Clone SPM508 Host and Isotype: Mouse IgG1 kappa
Anti-Human and Rat (-) Kappa Light Chain Positive Control Sample: 293T, Raji or hPBL cells. Tonsil or Spleen
Cellular Localization of Antibody Cell surface, cytoplasmic, secreted
Buffer and Stabilizer: 10mM PBS with 0.05% BSA & 0.05% azide.
Antibody Concentration: 200ug/ml
Antibody Purification Method:Protein A/G Purified
Immunogen: Human B-Lymphoma Cells
Storage Conditions: Store at 2 to 8° C (refrigerate). Stable for 24 months when properly stored.

Kappa Light Chain Previously Observed Antibody Staining Patterns

Limitations and Warranty

enQuire Bio's Kappa Light Chain Anti-Human Monoclonal is available for Research Use Only. This antibody is guaranteed to work for a period of two years when properly stored.

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