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Anti-Lipoprotein-associated phospholipase A2 Antibody Clone PLA2G7-Q7

$ 448.00
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SKU: QDX22
Species: Human
Tested Applications: ?ELISA, CLIA, LFIA (Lateral Flow Immunoassay)
Available Conjugates: Unconjugated
Isotype: Mouse IgG2b
Mass Spec Validated?: Not MS Validated

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Datasheets and Documentation
Product Datasheet
SKU: QDX22-100ug
Lipoprotein-associated phospholipase A2 General Information
Alternate Names
Phospholipase A2 Group VII, Group-VIIA Phospholipase A2, LDL-PLA, LDL-PLA2, LDL-PLA(2), PAFAD
Curated Database and Bioinformatic Data
Gene SymbolPLA2G7
Entrez Gene ID7941
Ensemble Gene IDENSG00000146070
RefSeq Protein Accession(s)XP_005249465, NP_001161829, NP_005075
RefSeq mRNA Accession(s)NM_001168357, XR_001743639 NM_005084, XM_005249408
RefSeq Genomic Accession(s)NC_000006, NC_018917, NG_016204
UniProt ID(s)Q13093
UniGene ID(s)Q13093
HGNC ID(s)9040
Cosmic ID(s)PLA2G7
KEGG Gene ID(s)hsa:7941
PharmGKB ID(s)PA33368
General Description of Lipoprotein-associated phospholipase A2.
Lipoprotein-associated phospholipase A2 (Lp-PLA2) also known as platelet-activating factor acetylhydrolase (PAF-AH) is a phospholipase A2 enzyme in humans. Lp-PLA2 is a 45 kDa protein of 441 amino acids encoded by the gene. Some recent studies have shown that Lp-PLA2 is an independent risk marker for cardiovascular disease (CVD), including coronary heart disease (CHD), and ischemic stroke. In these studies, increased concentrations of Lp-PLA2 were seen in many people who were diagnosed with CHD and ischemic stroke, regardless of other risk factors. These findings make relatively the new test potentially useful among the growing number of cardiac risk markers used to determine a person's risk of developing CVD. Lp-PLA2 is specific for vascular inflammation and is a circulating measure of the progression of rupture-prone plaque. Following production by inflammatory cells, this enzyme cleaves oxidized phospholipids, generating pro-inflammatory molecules and oxidized fatty acids. Elevated Lp-PLA2 levels can predict the development of coronary artery disease in apparently healthy individuals and the risk of future adverse cardiac and cerebrovascular events. The Lp-PLA2 tests are meaningful for assessing risk of coronary artery disease and stroke.

Human Anti-Lipoprotein-associated phospholipase A2 Antibody Product Attributes

Species: Human
Tested Applications: ?ELISA, CLIA, LFIA (Lateral Flow Immunoassay).
Clonality: Monoclonal
Anti-Lipoprotein-associated phospholipase A2 Antibody Clone: PLA2G7-Q7
Clone PLA2G7-Q7 Host and Isotype: Mouse IgG2b
Buffer and Stabilizer: PBS (pH 7.4)
Antibody Purification Method:Protein G
Storage Conditions: Upon receipt aliquot and store at -20C or -80C. Avoid repeated freeze.

Lipoprotein-associated phospholipase A2 Previously Observed Antibody Staining Patterns

Limitations and Warranty

enQuire Bio's Anti-Human Lipoprotein-associated phospholipase A2 Antibody is available for Research Use Only. This antibody is guaranteed to work for a period of two years when properly stored.

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Anti-Lipoprotein-associated phospholipase A2 Antibody Clone PLA2G7-Q7