Anti-Major Vault Protein Antibody Clone SPM280

Observed Antibody Staining Data By Tissue Type:

Variations in Major Vault Protein antibody staining intensity in immunohistochemistry on tissue sections are present across different anatomical locations. An intense signal was observed in glandular cells in the appendix, respiratory epithelial cells in the bronchus, glandular cells in the colon, peripheral nerve/ganglion in colon, glandular cells in the duodenum, macrophages in lung, respiratory epithelial cells in the nasopharynx, glandular cells in the rectum and small intestine, Leydig cells in the testis and urothelial cells in the urinary bladder. More moderate antibody staining intensity was present in glandular cells in the appendix, respiratory epithelial cells in the bronchus, glandular cells in the colon, peripheral nerve/ganglion in colon, glandular cells in the duodenum, macrophages in lung, respiratory epithelial cells in the nasopharynx, glandular cells in the rectum and small intestine, Leydig cells in the testis and urothelial cells in the urinary bladder. Low, but measureable presence of Major Vault Protein could be seen inhematopoietic cells in the bone marrow, Purkinje cells in the cerebellum, endothelial cells in the cerebral cortex, neuropil in cerebral cortex, glandular cells in the cervix, uterine, cells in the endometrial stroma in endometrium, glandular cells in the endometrium and epididymis, neuronal cells in the hippocampus, bile duct cells in the liver, germinal center cells in the lymph node, non-germinal center cells in the lymph node, exocrine glandular cells in the pancreas, glandular cells in the parathyroid gland, salivary gland and seminal vesicle, keratinocytes in skin, fibroblasts in mesenchymal tissue, peripheral nerve in mesenchymal tissue, cells in the white pulp in spleen and squamous epithelial cells in the tonsil and vagina. We were unable to detect Major Vault Protein in other tissues. Disease states, inflammation, and other physiological changes can have a substantial impact on antibody staining patterns. These measurements were all taken in tissues deemed normal or from patients without known disease.