Formalin-fixed, paraffin-embedded human Melanoma stained with Melanoma Marker Monoclonal Antibody (A13 + T311 + HMB45).

Anti-Melanoma Marker Antibody Clone A103 + HMB45 + T311

Name: Anti-Melanoma Marker Antibody Clone A103 + HMB45 + T311
Brand: enQuire Bio
Price: 429 USD
Availability: InStock

$ 429.00

Please Select Product Options Below To View The Catalog Number.

SKU: MSM2-702
Species: Human
Tested Applications: Immunohistochemistry (IHC)
Available Conjugates: Unconjugated
Isotype: Mouse IgG1 IgG2a kappa
Mass Spec Validated?: Not MS Validated

Product Number	Description	Price
MSM2-702-P1	Size: 100 ug, Tag: Unconjugated

Shipping Information

In Stock.

Flat Rate Shipping Anywhere in the US: $45

Datasheets and Documentation

Product Datasheet

Certificate of Analysis and Tags (Coming Soon)

SKU: MSM2-702-P1

Melanoma Marker General Information
Alternate Names
Melanoma antigen recognized by T-cells 1 (MART-1), MLAN-A, TYR, PMEL17, anti-Melanoma antigen recognized by T-cells 1 (MART-1) antibody, anti-MLAN-A antibody, anti-TYR antibody, anti-PMEL17 antibody
Molecular Weight
20-22kDa (doublet) (MART); 70-80kDa (Tyrosinase); 90-100kDa (gp100)
Chromosomal Location
Multiple
Curated Database and Bioinformatic Data
Entrez Gene ID	, 7299, 6490
Ensemble Gene ID	, ENSG00000077498, ENSG00000185664
RefSeq Protein Accession(s)	, XP_011541272, NP_000363, NP_001186982, XP_006719632, NP_001307050, NP_008859, XP_011536987, NP_001186983, NP_001307051
RefSeq mRNA Accession(s)	, NM_000372, XM_011542970, , XM_006719569, NM_001320122, NM_001200053, XM_011538685, NM_001320121, NM_006928 NM_001200054
RefSeq Genomic Accession(s)	, NC_000011, NG_008748, NC_018922, NC_000012, NC_018923, NG_028086
UniProt ID(s)	, P14679, L8B082, P40967
UniGene ID(s)	, P14679, L8B082, P40967
HGNC ID(s)	, 12442, 10880
Cosmic ID(s)	, TYR, PMEL
KEGG Gene ID(s)	, hsa:7299, hsa:6490
PharmGKB ID(s)	, PA37095, PA35781
General Description of Melanoma Marker.
This antibody cocktail recognizes three melanoma-specific proteins, which include MART-1, Tyrosinase, gp100. MART-1 is a newly identified melanocyte differentiation antigen recognized by autologous cytotoxic T lymphocytes. Tyrosinase is one of the targets for cytotoxic T-cell recognition in melanoma patients. The function of gp100 is not known but it is reported to be a useful marker for melanocytes, melanomas. This cocktail of three markers is designed for extremely sensitive labeling of formalin-fixed, paraffin-embedded melanomas, other tumors showing melanocytic differentiation.

Human Anti-Melanoma Marker Antibody Product Attributes

Species: Human

Tested Applications: Immunohistochemistry (IHC).

Application Notes: Immunohistochemistry (IHC) (Formalin-fixed) (0.5-1.0ug of antibody/ml for 30 minutes at RT)

Clonality: Monoclonal

Anti-Melanoma Marker Antibody Clone: A103 + HMB45 + T311

Clone A103 + HMB45 + T311 Host and Isotype: Mouse IgG1 IgG2a kappa

Anti-Human Melanoma Marker Positive Control Sample: SK-MEL-13, SK-MEL-19 Melanoma cell lines; Melanomas

Cellular Localization of Antibody Cytoplasmic

Buffer and Stabilizer: 10mM PBS with 0.05% BSA & 0.05% azide.

Antibody Concentration: 200ug/ml

Antibody Purification Method:Protein A/G Purified

Immunogen: Recombinant hMART-1 protein (A103); Recombinant tyrosinase protein (T311); Extract of pigmented melanoma metastases from lymph nodes (HMB45)

Storage Conditions: Store at 2 to 8Â° C (refrigerate). Stable for 24 months when properly stored.

Melanoma Marker Previously Observed Antibody Staining Patterns

Limitations and Warranty

enQuire Bio's Melanoma Marker Anti-Human Monoclonal is available for Research Use Only. This antibody is guaranteed to work for a period of two years when properly stored.

There are no reviews yet.