Formalin-fixed, paraffin-embedded Human Pancreas stained with MRP1/ABCC1 Monoclonal Antibody (MRP1/1343).
Formalin-fixed, paraffin-embedded Human Pancreas stained with MRP1/ABCC1 Monoclonal Antibody (MRP1/1343).Formalin-fixed, paraffin-embedded Human Duodenum stained with MRP1/ABCC1 Monoclonal Antibody (MRP1/1343).Formalin-fixed, paraffin-embedded Human Rectal Carcinoma stained with MRP1/ABCC1 Monoclonal Antibody (MRP1/1343).Formalin-fixed, paraffin-embedded Human Colon Carcinoma stained with MRP1/ABCC1 Monoclonal Antibody (MRP1/1343).

Anti-MRP1 / ABCC1 Antibody Clone MRP1/1343

$ 118.00$ 418.00
Please Select Product Options Below To View The Catalog Number.

SKU: 4363-MSM1
Species: Human
Tested Applications: Immunohistochemistry (IHC)
Available Conjugates: Unconjugated
Isotype: Mouse IgG1
Mass Spec Validated?: Not MS Validated

Product NumberDescriptionPrice
4363-MSM1-P0 Size: 20 ug, Tag: Unconjugated $ 118.00
4363-MSM1-P1 Size: 100 ug, Tag: Unconjugated $ 298.00
4363-MSM1-P2 Size: 200 ug, Tag: Unconjugated $ 418.00
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In Stock.
Flat Rate Shipping Anywhere in the US: $45
Datasheets and Documentation
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SKU: 4363-MSM1-P0
MRP1 / ABCC1 General Information
Alternate Names
Multidrug resistance-associated protein 1, MRP1, ABCC1
Molecular Weight
190kDa
Chromosomal Location
16p13.11
Curated Database and Bioinformatic Data
Gene SymbolABCC1
Entrez Gene ID4363
Ensemble Gene IDENSG00000103222, ENSG00000278183
RefSeq Protein Accession(s)XP_011520800, XP_016878728, NP_004987, XP_016878729, XP_011520799, XP_016878726, XP_016878730, XP_016878732, XP_016878727, XP_016878731
RefSeq mRNA Accession(s)XM_017023240, NM_019901, XM_017023242, NM_019862, XM_011522497, XM_017023241, NM_004996 NM_019900, XM_017023237, NM_019902, XM_011522498, XM_017023243, NM_019899, XM_017023238, XM_017023239, NM_019898
RefSeq Genomic Accession(s)NG_187607, NC_018927, NG_028268, NC_000016
UniProt ID(s)P33527
UniGene ID(s)P33527
HGNC ID(s)51
Cosmic ID(s)ABCC1
KEGG Gene ID(s)hsa:4363
PharmGKB ID(s)PA244
General Description of MRP1 / ABCC1.
The two members of the large family of ABC transporters known to confer multidrug resistance in human cancer cells are the MDR1 P-glycoprotein and the multidrug-resistance protein MRP1. MRP1 is an integral membrane protein that contains an MDR-like core, an N-terminal membrane-bound region and a cytoplasmic linker, and it is expressed in various cerebral cells, as well as in lung, testis and peripheral blood.

Human Anti-MRP1 / ABCC1 Antibody Product Attributes

Species: Human
Tested Applications: Immunohistochemistry (IHC).
Clonality: Monoclonal
Anti-MRP1 / ABCC1 Antibody Clone: MRP1/1343
Clone MRP1/1343 Host and Isotype: Mouse IgG1
Anti-Human MRP1 / ABCC1 Positive Control Sample: A549 cells. Colon, Endometrium, Ovary. Testis or Tonsil.
Cellular Localization of Antibody Cytoplasmic and Cell Surface
Buffer and Stabilizer: 10mM PBS with 0.05% BSA and 0.05% Azide
Antibody Concentration: 200 ug/ml
Antibody Purification Method:Protein A/G Purified
Immunogen: Recombinant human full-length ABCC1
Storage Conditions: Store at 2 to 8° C (refrigerate). Stable for 24 months when properly stored.

MRP1 / ABCC1 Previously Observed Antibody Staining Patterns

Observed Subcellular, Organelle Specific Staining Data:

Anti-abcc1 antibody staining is expected to be primarily localized to the plasma membrane.

Observed Antibody Staining Data By Tissue Disease Status:

Tissues from cancer patients, for instance, have their own distinct pattern of MRP1 / ABCC1 expression as measured by anti-MRP1 / ABCC1 antibody immunohistochemical staining. The average level of expression by tumor is summarized in the table below. The variability row represents patient to patient variability in IHC staining.

Sample Type breast cancer carcinoid cervical cancer colorectal cancer endometrial cancer glioma head and neck cancer liver cancer lung cancer lymphoma melanoma ovarian cancer pancreatic cancer prostate cancer renal cancer skin cancer stomach cancer testicular cancer thyroid cancer urothelial cancer
Signal Intensity - - - - + - - - - - + - - - - - - - + -
ABCC1 Variability + ++ + + ++ ++ ++ + + ++ ++ + + + ++ + + + ++ +

Limitations and Warranty

enQuire Bio's MRP1 / ABCC1 Anti-Human Monoclonal is available for Research Use Only. This antibody is guaranteed to work for a period of two years when properly stored.

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Anti-MRP1 / ABCC1 Antibody Clone MRP1/1343

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