Immunohistochemical staining of Mucin 5AC/Gastric Mucin  of human FFPE tissue followed by incubation with HRP labeled secondary and development with DAB substrate.

Mucin 5AC/Gastric Mucin [45M1 ] Antibody (cGMP).

$ 135.00$ 605.00
Please Select Product Options Below To View The Catalog Number.

SKU: QIVD299
Species: Human
Tested Applications: IHC [IVD]
Available Conjugates:
Isotype: Mouse IgG1, kappa

Product NumberDescriptionPrice
QIVD299-0.1ml Size: 0.1 ml, Format: Concentrate $ 135.00
QIVD299-0.5ml Size: 0.5 ml, Format: Concentrate $ 375.00
QIVD299-1ml Size: 1 ml, Format: Concentrate $ 605.00
QIVD299-6ml Size: 6 ml, Format: Predilute $ 265.00
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Datasheets and Documentation
Product Datasheet
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SKU: QIVD299-0.1ml
Mucin 5AC/Gastric Mucin General Information
Alternate Names
Molecular Weight
585.6 kDa
Chromosomal Location
p15.5 [chr: 11] [chr_start: 1157953] [chr_end: 1201138] [strand: 1]; [chr: CHR_HG107_PATCH] [chr_start: 1159911] [chr_end: 1203106] [strand: 1]
Curated Database and Bioinformatic Data
Gene SymbolMUC5AC
Entrez Gene ID4586
RefSeq Protein Accession(s)NP_001291288
RefSeq mRNA Accession(s)NM_017511; NM_001304359
RefSeq Genomic Accession(s)NW_015148966; NC_000011
UniProt ID(s)P98088
KEGG Gene ID(s)hsa:4586
General Description of Mucin 5AC/Gastric Mucin .
This antibody reacts with a 1000 kDa protein and recognizes the peptide core of gastric mucin M1. Mucins are high molecular weight glycoproteins with 80% carbohydrates and 20% core protein. Gastric mucin M1 antigen is found in columnar mucus cells of surface gastric epithelium and in goblet cells of the fetal and precancerous colon but not in normal colon. Resurgence of gastric mucin during colonic carcinogenesis is suggestive of either re-expression of the peptide core of gastric mucin in the adult colon or changes in the glycosylation pattern of mucin, which expose the hidden M1 antigen.

Antibody (Suitable for clinical applications)

Sample Type: FFPE Patient Samples.
Tested Applications: IHC. Approved for In Vitro Diagnostic Procedures on FFPE tissues. For tissue collection recommendations, please see datasheet sent with product.
Application Notes
Specification Recommendation
Recommended Dilution (Conc) 1:50-1:200
Pretreatment No Pretreatment Required
Incubation Parameters 30 min at Room Temperature

Prior to use, inspect vial for the presence of any precipitate or other unusual physical properties. These can indicate that the antibody has degraded and is no longer suitable for patient samples. Please run positive and negative controls simultaneously with all patient samples to account and control for errors in laboratory procedure. Use of methods or materials not recommended by enQuire Bio including change to dilution range and detection system should be routinely validated by the user.

Clonality: Monoclonal
Anti-Mucin 5AC/Gastric Mucin Antibody Clone: 45M1
Host and Isotype: Mouse IgG1, kappa
Recommended Positive Control Sample: Stomach
Cellular Localization of Antibody 45M1 Staining: Cytoplasmic, cell surface
Buffer and Stabilizer: PBS with 1% BSA and 0.05% NaN3
Antibody Concentration: Lot specific. Plese contact tech support for data.
Immunogen: BALB/C mice were injected with M1 mucin preparation from the fluid of an ovarian mucinous cyst belonging to an O Le (a-b) patient.
Storage Conditions: This antibody should be stored refrigerated (2-8°C). This product should not be used past the expiration date printed on the vial.

Mucin 5AC/Gastric Mucin Information for Pathologists

Limitations and Warranty

This antibody is manufactured in accordance with clinical good manufacturing practices in an ISO13485:2016 certified production facility. It is intended for multiple uses including in vitro diagnostic use and research use only applications. Please see vial label for expiration date. We strive to always deliver antibodies with a shelf life of at least two years.

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Mucin 5AC/Gastric Mucin [45M1 ] Antibody (cGMP).