Immunohistochemical staining of Myeloperoxidase  of human FFPE tissue followed by incubation with HRP labeled secondary and development with DAB substrate.

Myeloperoxidase [Polyclonal] Antibody (cGMP).

$ 158.00$ 538.00
Please Select Product Options Below To View The Catalog Number.

SKU: QIVD170
Species: Human
Tested Applications: IHC [IVD]
Available Conjugates:
Isotype: Rabbit Undetermined

Product NumberDescriptionPrice
QIVD170-0.1ml Size: 0.1 ml, Format: Concentrate $ 135.00
QIVD170-0.5ml Size: 0.5 ml, Format: Concentrate $ 285.00
QIVD170-1ml Size: 1 ml, Format: Concentrate $ 475.00
QIVD170-6ml Size: 6 ml, Format: Predilute $ 205.00
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Datasheets and Documentation
Product Datasheet
Certificate of Analysis and Tags (Coming Soon)
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SKU: QIVD170-0.1ml
Myeloperoxidase General Information
Alternate Names
Molecular Weight
83.9 kDa
Chromosomal Location
q22 [chr: 17] [chr_start: 58269856] [chr_end: 58280935] [strand: -1]
Curated Database and Bioinformatic Data
Gene SymbolMPO
Entrez Gene ID4353
RefSeq Protein Accession(s)NP_000241
RefSeq mRNA Accession(s)NM_000250;
RefSeq Genomic Accession(s)NG_009629; NC_000017
UniProt ID(s)P05164
PharmGKB ID(s)PA243
KEGG Gene ID(s)hsa:4353
Associated Diseases (KEGG IDs)Myeloperoxidase deficiency (MPOD) [MIM:254600]: A disorder characterized by decreased myeloperoxidase activity in neutrophils and monocytes that results in disseminated candidiasis. {ECO:0000269|PubMed:7904599, ECO:0000269|PubMed:8142659, ECO:0000269|PubMed:8621627, ECO:0000269|PubMed:9354683, ECO:0000269|PubMed:9637725}. The disease is caused by mutations affecting the gene represented in this entry.
General Description of Myeloperoxidase .
This antibody reacts with human myeloperoxidase. It stains granules of neutrophils, granulocytes in spleen, bone marrow, tonsil and blood smears.

Antibody (Suitable for clinical applications)

Sample Type: FFPE Patient Samples.
Tested Applications: IHC. Approved for In Vitro Diagnostic Procedures on FFPE tissues. For tissue collection recommendations, please see datasheet sent with product.
Application Notes
Specification Recommendation
Recommended Dilution (Conc) 1:25-1:100
Pretreatment Citrate Buffer pH 6.0
Incubation Parameters 30 min at Room Temperature

Prior to use, inspect vial for the presence of any precipitate or other unusual physical properties. These can indicate that the antibody has degraded and is no longer suitable for patient samples. Please run positive and negative controls simultaneously with all patient samples to account and control for errors in laboratory procedure. Use of methods or materials not recommended by enQuire Bio including change to dilution range and detection system should be routinely validated by the user.

Clonality: Polyclonal
Anti-Myeloperoxidase Antibody Clone: Polyclonal
Host and Isotype: Rabbit Undetermined
Recommended Positive Control Sample: Tonsil
Cellular Localization of Antibody Polyclonal Staining: Cytoplasmic
Buffer and Stabilizer: PBS with 1% BSA and 0.05% NaN3
Antibody Concentration: Lot specific. Plese contact tech support for data.
Immunogen: Myeloperoxidase isolated from human granulocytes.
Storage Conditions: This antibody should be stored refrigerated (2-8°C). This product should not be used past the expiration date printed on the vial.

Myeloperoxidase Information for Pathologists

Summary:

Staining is either immunohistochemistry (IHC) or enzyme cytochemistry - enzyme cytochemistry is most sensitive and specific stain for myeloid leukemias and granulocytic sarcoma. Stains neutrophils strongly (diffuse granular pattern), other granulocytes variably. Microscopic (histologic) images Missing Image. Myeloid sarcoma of breast.

Limitations and Warranty

This antibody is manufactured in accordance with clinical good manufacturing practices in an ISO13485:2016 certified production facility. It is intended for multiple uses including in vitro diagnostic use and research use only applications. Please see vial label for expiration date. We strive to always deliver antibodies with a shelf life of at least two years.

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Myeloperoxidase [Polyclonal] Antibody (cGMP).