Formalin-fixed, paraffin-embedded human Parathyroid stained with PTH Recombinant Rabbit Monoclonal Antibody (PTH/1717R).

Anti-Parathyroid Hormone Antibody Clone PTH/1717R

Name: Anti-Parathyroid Hormone Antibody Clone PTH/1717R
Brand: enQuire Bio
Price: 199 USD
Availability: InStock

$ 228.00 – $ 618.00

Please Select Product Options Below To View The Catalog Number.

SKU: 5741-RBM7
Species: Human
Tested Applications: Immunohistochemistry (IHC)
Available Conjugates: Unconjugated
Isotype: Rabbit IgG kappa
Mass Spec Validated?: Not MS Validated

Product Number	Description	Price
5741-RBM7-P0	Size: 20 ug, Tag: Unconjugated	$ 199.00
5741-RBM7-P1	Size: 100 ug, Tag: Unconjugated	$ 429.00
5741-RBM7-P2	Size: 200 ug, Tag: Unconjugated	$ 549.00

Shipping Information

In Stock.

Flat Rate Shipping Anywhere in the US: $45

Datasheets and Documentation

Product Datasheet

Certificate of Analysis and Tags (Coming Soon)

SKU: 5741-RBM7-P0

Parathyroid Hormone General Information
Alternate Names
Parathyroid Hormone, PTH
Molecular Weight
9kDa
Chromosomal Location
11p15.3-p15.1
Curated Database and Bioinformatic Data
Gene Symbol	PTH
Entrez Gene ID	5741
Ensemble Gene ID	ENSG00000152266
RefSeq Protein Accession(s)	NP_000306, NP_001303281
RefSeq mRNA Accession(s)	NM_000315, NM_001316352
RefSeq Genomic Accession(s)	NG_008962, NC_018922, NC_000011
UniProt ID(s)	P01270
UniGene ID(s)	P01270
HGNC ID(s)	9606
Cosmic ID(s)	PTH
KEGG Gene ID(s)	hsa:5741
PharmGKB ID(s)	PA33951
General Description of Parathyroid Hormone.
Epitope of this MAb maps in the N-terminus of PTH, a hormone produced by the parathyroid gland that regulates the concentration of calcium and phosphorus in extracellular fluid. This hormone elevates blood Ca2+ levels by dissolving the salts in bone and preventing their renal excretion. It is produced in the parathyroid gland as an 84 amino acid single chain polypeptide. It can also be secreted as N-terminal truncated fragments or C-terminal fragments after intracellular degradation, as in case of hypercalcemia. Defects in this gene are a cause of familial isolated hypoparathyroidism (FIH); also called autosomal dominant hypoparathyroidism or autosomal dominant hypocalcemia. FIH is characterized by hypocalcemia and hyperphosphatemia due to inadequate secretion of parathyroid hormone. Symptoms are seizures, tetany and cramps. FIH exist both as autosomal dominant and recessive forms of hypoparathyroidism.

Human Anti-Parathyroid Hormone Antibody Product Attributes

Species: Human

Tested Applications: Immunohistochemistry (IHC).

Clonality: Recombinant Monoclonal

Anti-Parathyroid Hormone Antibody Clone: PTH/1717R

Clone PTH/1717R Host and Isotype: Rabbit IgG kappa

Anti-Human Parathyroid Hormone Positive Control Sample: Human parathyroid gland carcinoma

Cellular Localization of Antibody Cytoplasmic and Secreted

Buffer and Stabilizer: 10mM PBS with or without 0.05% BSA & 0.05% azide.

Antibody Concentration: 200ug/ml

Antibody Purification Method:Protein A/G Purified

Immunogen: Recombinant human PTH protein N-terminal fragment

Storage Conditions: Store at 2 to 8Â° C (refrigerate). Stable for 24 months when properly stored.

Parathyroid Hormone Previously Observed Antibody Staining Patterns

Observed Antibody Staining Data By Tissue Type:

Variations in Parathyroid Hormone antibody staining intensity in immunohistochemistry on tissue sections are present across different anatomical locations. An intense signal was observed in glandular cells in the parathyroid gland. More moderate antibody staining intensity was present in glandular cells in the parathyroid gland. Low, but measureable presence of Parathyroid Hormone could be seen in. We were unable to detect Parathyroid Hormone in other tissues. Disease states, inflammation, and other physiological changes can have a substantial impact on antibody staining patterns. These measurements were all taken in tissues deemed normal or from patients without known disease.

Limitations and Warranty

enQuire Bio's Parathyroid Hormone Recombinant Monoclonal is available for Research Use Only. This antibody is guaranteed to work for a period of two years when properly stored.

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