FFPE human renal cell carcinoma sections stained with 100 ul anti-PAX8 (clone PAX8/1491) at 1:300. HIER epitope retrieval prior to staining was performed in 10mM Citrate, pH 6.0.Formalin-fixed, paraffin embedded human thyroidal carcinoma sections stained with 100 ul anti-PAX8 (clone PAX8/1491) at 1:300. HIER epitope retrieval prior to staining was performed in 10mM Citrate, pH 6.0.Western Blot Analysis (A) Recombinant Protein (B) Raji Cell Lysate Using PAX8 Monoclonal Antibody (PAX8/1491).

Anti-PAX8 Antibody Clone PAX8/1491

$ 199.00$ 459.00
Please Select Product Options Below To View The Catalog Number.

SKU: 7849-MSM1
Species: Human
Tested Applications: Western Blot
Available Conjugates: Unconjugated
Isotype: Mouse IgG2b
Mass Spec Validated?: Not MS Validated

Product NumberDescriptionPrice
7849-MSM1-P0 Size: 20 ug, Tag: Unconjugated $ 199.00
7849-MSM1-P1 Size: 100 ug, Tag: Unconjugated $ 429.00
7849-MSM1-P2 Size: 200 ug, Tag: Unconjugated $ 459.00
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Datasheets and Documentation
Product Datasheet
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SKU: 7849-MSM1-P0
PAX8 General Information
Alternate Names
Paired box gene 8, PAX8
Molecular Weight
Chromosomal Location
Curated Database and Bioinformatic Data
Gene SymbolPAX8
Entrez Gene ID7849
Ensemble Gene IDENSG00000125618
RefSeq Protein Accession(s)NP_003457, NP_039246, XP_011510093, XP_011510096, XP_011510094, XP_011510095, XP_016860368, NP_039247, XP_011510092, NP_054698, XP_016860367
RefSeq mRNA Accession(s)NM_013951, XM_017004878, XM_011511790, XR_923021, XM_011511793, NM_013992 NM_013953, XM_011511791, XM_011511792, XM_017004879, XM_011511794, NM_003466, NM_013952
RefSeq Genomic Accession(s)NC_018913, NG_012384, NC_000002
UniProt ID(s)R9W7C9, A0A024R4X8, A0A024R531, A0A024R524, Q06710
UniGene ID(s)R9W7C9, A0A024R4X8, A0A024R531, A0A024R524, Q06710
HGNC ID(s)8622
Cosmic ID(s)PAX8
KEGG Gene ID(s)hsa:7849
PharmGKB ID(s)PA32962
General Description of PAX8.
Recognizes a protein of 62kDa, identified as PAX8. It is a member of the paired box (PAX) family of transcription factors. This nuclear protein is involved in thyroid follicular cell development and expression of thyroid-specific genes. Mutations in this gene have been associated with thyroid dysgenesis, thyroid follicular carcinomas, and atypical thyroid adenomas. PAX-8 is expressed in the thyroid (and associated carcinomas), non-ciliated mucosal cells of the fallopian tubes, and simple ovarian inclusion cysts, but not normal ovarian surface epithelial cells. PAX-8 is expressed in a high percentage of ovarian serous, endometrioid, and clear cell carcinomas, but only rarely in primary ovarian mucinous adenocarcinomas. PAX-8 expression is reported in renal tubules as well as renal cell carcinoma, nephroblastoma, and seminoma. PAX-8 antibody may be used as an additional immunohistochemical marker for renal epithelial tumors.

Human Anti-PAX8 Antibody Product Attributes

Species: Human
Tested Applications: Western Blot.
Clonality: Monoclonal
Anti-PAX8 Antibody Clone: PAX8/1491
Clone PAX8/1491 Host and Isotype: Mouse IgG2b
Anti-Human PAX8 Positive Control Sample: Raji cells. Renal Cell Carcinoma (RCC)
Cellular Localization of Antibody Nuclear
Buffer and Stabilizer: 10mM PBS with 0.05% BSA and 0.05% Azide
Antibody Concentration: 200 ug/ml
Antibody Purification Method:Protein A/G Purified
Immunogen: Recombinant human PAX8 fragment (aa60-261)
Storage Conditions: Store at 2 to 8° C (refrigerate). Stable for 24 months when properly stored.

PAX8 Previously Observed Antibody Staining Patterns

Observed Subcellular, Organelle Specific Staining Data:

Anti-PAX8 antibody staining is expected to be primarily localized to the nucleoplasm.

Limitations and Warranty

enQuire Bio's PAX8 Anti-Human Monoclonal is available for Research Use Only. This antibody is guaranteed to work for a period of two years when properly stored.

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Anti-PAX8 Antibody Clone PAX8/1491

https://enquirebio.com/wp-content/uploads/2019/01/Anti-PAX8 Specificity Assay (Array)-300x121.jpghttps://enquirebio.com/wp-content/uploads/2019/01/PAX8 IHC human Renal Cell Carcinoma (PAX8 1491)-300x225.jpghttps://enquirebio.com/wp-content/uploads/2019/01/PAX8 IHC human Thyroidal Carcinoma (PAX8 1491)-300x225.jpghttps://enquirebio.com/wp-content/uploads/2019/01/PAX8 Antibody SDS-PAGE Gel-243x300.jpghttps://enquirebio.com/wp-content/uploads/2019/01/PAX8 Western rhPAX8 and Raji Cell-150x300.jpghttps://enquirebio.com/wp-content/uploads/2017/10/enQuire-Bio-7849-MSM1-P0-anti-PAX8-antibody.jpeg