Formalin-fixed, paraffin-embedded human Prostate Carcinoma stained with PSA Monoclonal Antibody (KLK3/81).
Formalin-fixed, paraffin-embedded human Prostate Carcinoma stained with PSA Monoclonal Antibody (KLK3/81).

Anti-Prostate Specific Antigen Antibody Clone KLK3/801

$ 298.00
Please Select Product Options Below To View The Catalog Number.

SKU: 354-MSM2
Species: Human
Tested Applications: Flow Cytometry, Immunofluorescence, Immunohistochemistry (IHC)
Available Conjugates: Unconjugated
Isotype: Mouse IgG1 kappa
Mass Spec Validated?: Not MS Validated

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In Stock: 1-2 Day Lead Time.
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Datasheets and Documentation
Product Datasheet
SKU: 354-MSM2-P1
Prostate Specific Antigen General Information
Alternate Names
Prostate-specific antigen, PSA, gamma-seminoprotein, kallikrein-3, KLK3
Molecular Weight
33-34kDa
Chromosomal Location
19q13.33
Curated Database and Bioinformatic Data
Gene SymbolKLK3
Entrez Gene ID354
Ensemble Gene IDENSG00000142515
RefSeq Protein Accession(s)NP_001025218, NP_001025219, NP_001639
RefSeq mRNA Accession(s)NM_001648, NM_001030047, NM_001030050 NM_001030048, NM_001030049
RefSeq Genomic Accession(s)NC_018930, NG_011653, NC_000019,
UniProt ID(s)Q546G3, P07288
UniGene ID(s)Q546G3, P07288
HGNC ID(s)6364
Cosmic ID(s)KLK3
KEGG Gene ID(s)hsa:354
PharmGKB ID(s)PA164741810
General Description of Prostate Specific Antigen.
Recognizes a single protein of 33-34kDa, identified as the prostate specific antigen (PSA). This MAb is highly specific to PSA, stains prostatic secretory, ductal epithelium in both normal, neoplastic tissues. PSA is a chymotrypsin-like serine protease (kallikrein family) exclusively produced by the prostate epithelium,, abundant in seminal fluid. PSA can be detected in the sera of patients with prostatic carcinoma. It is predominantly complexed to a liver-derived serine protease inhibitor, alpha-1-antichymotrypsin (ACT). A higher proportion of serum PSA is complexed to ACT in prostate cancer than in benign prostate hyperplasia.

Human Anti-Prostate Specific Antigen Antibody Product Attributes

Species: Human
Tested Applications: Flow Cytometry, Immunofluorescence, Immunohistochemistry (IHC).
Application Notes: Flow Cytometry (0.5-1ug of antibody/million cells in 0.1ml), Immunofluorescence (0.5-1ug of antibody/ml), Immunohistochemistry (IHC) (Formalin-fixed) (0.25-0.5ug of antibody/ml for 30 minutes at RT)
Clonality: Monoclonal
Anti-Prostate Specific Antigen Antibody Clone: KLK3/801
Clone KLK3/801 Host and Isotype: Mouse IgG1 kappa
Anti-Human Prostate Specific Antigen Positive Control Sample: PC12 cells or normal prostate or prostate carcinoma
Cellular Localization of Antibody Cytoplasmic
Buffer and Stabilizer: 10mM PBS with 0.05% BSA & 0.05% azide.
Antibody Concentration: 200ug/ml
Antibody Purification Method:Protein A/G Purified
Immunogen: Recombinant full-length human KLK3 protein
Storage Conditions: Store at 2 to 8° C (refrigerate). Stable for 24 months when properly stored.

Prostate Specific Antigen Previously Observed Antibody Staining Patterns

Limitations and Warranty

enQuire Bio's Prostate Specific Antigen Anti-Human Monoclonal is available for Research Use Only. This antibody is guaranteed to work for a period of two years when properly stored.

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