Human Anti-Protocadherin FAT2 Antibody Product Attributes
Species: Human
Tested Applications: Immunohistochemistry (IHC).
Clonality: Monoclonal
Anti-Protocadherin FAT2 Antibody Clone: 8C5
Clone 8C5 Host and Isotype: Mouse IgG1 kappa
Anti-Human Protocadherin FAT2 Positive Control Sample: Esophagus, Cervix, Uterus, Tonsil or Cerebellum.
Cellular Localization of Antibody <8C5 Staining: Cell Surface
Buffer and Stabilizer: 10mM PBS with 0.05% BSA and 0.05% Azide
Antibody Concentration: 200 ug/ml
Antibody Purification Method:Protein A/G Purified
Immunogen: Purified recombinant human FAT2 fusion protein
Storage Conditions: Store at 2 to 8° C (refrigerate). Stable for 24 months when properly stored.
Protocadherin FAT2 Previously Observed Antibody Staining Patterns
Observed Antibody Staining Data By Tissue Type:
Variations in Protocadherin FAT2 antibody staining intensity in immunohistochemistry on tissue sections are present across different anatomical locations. An intense signal was observed in cells in the granular layer in cerebellum, epidermal cells in the skin, squamous epithelial cells in the cervix and uterine, tonsil and vagina. More moderate antibody staining intensity was present in cells in the granular layer in cerebellum, epidermal cells in the skin, squamous epithelial cells in the cervix and uterine, tonsil and vagina. Low, but measureable presence of Protocadherin FAT2 could be seen inkeratinocytes in skin. We were unable to detect Protocadherin FAT2 in other tissues. Disease states, inflammation, and other physiological changes can have a substantial impact on antibody staining patterns. These measurements were all taken in tissues deemed normal or from patients without known disease.Observed Antibody Staining Data By Tissue Disease Status:
Tissues from cancer patients, for instance, have their own distinct pattern of Protocadherin FAT2 expression as measured by anti-Protocadherin FAT2 antibody immunohistochemical staining. The average level of expression by tumor is summarized in the table below. The variability row represents patient to patient variability in IHC staining.Sample Type | breast cancer | carcinoid | cervical cancer | colorectal cancer | endometrial cancer | glioma | head and neck cancer | liver cancer | lung cancer | lymphoma | melanoma | ovarian cancer | pancreatic cancer | prostate cancer | renal cancer | skin cancer | stomach cancer | testicular cancer | thyroid cancer | urothelial cancer |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
Signal Intensity | - | - | - | - | - | - | - | - | - | - | - | - | - | - | - | - | - | - | - | + |
FAT2 Variability | + | + | + | + | + | + | + | + | + | + | + | + | + | + | + | + | + | + | + | ++ |
Limitations and Warranty
enQuire Bio's Protocadherin FAT2 Anti-Human Monoclonal is available for Research Use Only. This antibody is guaranteed to work for a period of two years when properly stored.
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