Anti-Human S100A1 Monoclonal [Clone S100A1/1012]

$ 429.00
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SKU: 6271-MSM2
Species: Human ;Mouse ;Rat ;Cow
Tested Applications: Flow Cytometry, Immunofluorescence, Western Blot, Immunohistochemistry (IHC)
Available Conjugates: Unconjugated
Isotype: Mouse IgG2a, kappa
Mass Spec Validated?:

Product NumberDescriptionPrice
6271-MSM2-P1 Size: 100 ug, Tag: Unconjugated
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SKU: 6271-MSM2-P1
S100A1 General Information
Alternate Names
Molecular Weight
Chromosomal Location
Curated Database and Bioinformatic Data
Gene Symbol S100A1
Entrez Gene ID 6271
UniProt ID(s) P23297
General Description of S100A1.
The family of EF-hand type Ca2+-binding proteins includes calbindin, S-100 alpha, beta, calgranulins, B, C,, the parvalbumin family members, including parvalbumin alpha, parvalbumin beta. The S-100 protein is involved in the regulation of cellular processes such as cell cycle progression, differentiation. S-100 protein may function in the activation of Ca2+ induced Ca2+ release, inhibition of microtubule assembly, inhibition of protein kinase C mediated phosphorylation. Two S-100 subunits, sharing 60% sequence identity, have been described as S-100 alpha chain, S-100 beta chain. Three S-100 dimeric forms have been characterized, differing in their subunit composition of two alpha chains, two beta chains or one alpha, one beta chain. S-100 localizes to the cytoplasm, nuclei of astrocytes, Schwann s cells, ependymomas, astrogliomas. S-100 is also detected in almost all benign naevi, malignant melanocytic tumours, in Langerhans cells in the skin. Calbindin, S-100 proteins, parvalbumin proteins are each expressed in neural tissues. In addition, S-100 alpha, beta are present in a variety of other tissues, calbindin is present in intestine, kidney.

Human ;Mouse ;Rat ;Cow Anti-S100A1 Antibody Product Attributes

Species: Human ;Mouse ;Rat ;Cow
Cross Reactivity:
Tested Applications: Flow Cytometry, Immunofluorescence, Western Blot, Immunohistochemistry (IHC).
Clonality: Monoclonal
Anti-S100A1 Antibody Clone: S100A1/1012
Clone S100A1/1012 Host and Isotype: Mouse IgG2a, kappa
Anti-Human ;Mouse ;Rat ;Cow S100A1 Positive Control Sample: Brain, Melanoma
Cellular Localization of Antibody <S100A1/1012 Staining: Cytoplasmic
Buffer and Stabilizer: 10mM PBS with 0.05% BSA & 0.05% azide.
Antibody Concentration: 200ug/ml
Antibody Purification Method:Protein A/G Purified
Immunogen: Recombinant full-length human S100A1 protein
Storage Conditions: Store at 2 to 8° C (refrigerate). Stable for 24 months when properly stored.

S100A1 Previously Observed Antibody Staining Patterns

Limitations and Warranty

This product is for Research Use Only. This product is guaranteed to work for a period of two years when stored at -70C or colder, and one year when aliquoted and stored at -20C.

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Anti-Human S100A1 Monoclonal [Clone S100A1/1012]