Human Anti-Thrombomodulin / CD141 Antibody Product Attributes
Species: Human
Tested Applications: Immunohistochemistry (IHC).
Clonality: Monoclonal
Anti-Thrombomodulin / CD141 Antibody Clone: THBD/1782
Clone THBD/1782 Host and Isotype: Mouse IgG2a kappa
Anti-Human Thrombomodulin / CD141 Positive Control Sample: THP1 Cells. Placenta, Angiosarcoma, Bladder or Cervical Carcinoma
Cellular Localization of Antibody Cell Surface ;Cytoplasmic
Buffer and Stabilizer: 10mM PBS with 0.05% BSA and 0.05% Azide
Antibody Concentration: 200 ug/ml
Antibody Purification Method:Protein A/G Purified
Immunogen: Recombinant human Thrombomodulin protein fragment (aa69-194)
Storage Conditions: Store at 2 to 8° C (refrigerate). Stable for 24 months when properly stored.
Thrombomodulin / CD141 Previously Observed Antibody Staining Patterns
Observed Subcellular, Organelle Specific Staining Data:
Anti-THBD antibody staining is expected to be primarily localized to the cytosol and nucleoplasm.Observed Antibody Staining Data By Tissue Type:
Variations in Thrombomodulin / CD141 antibody staining intensity in immunohistochemistry on tissue sections are present across different anatomical locations. Low, but measureable presence of Thrombomodulin / CD141 could be seen innon-germinal center cells in the lymph node and squamous epithelial cells in the tonsil. We were unable to detect Thrombomodulin / CD141 in other tissues. Disease states, inflammation, and other physiological changes can have a substantial impact on antibody staining patterns. These measurements were all taken in tissues deemed normal or from patients without known disease.Observed Antibody Staining Data By Tissue Disease Status:
Tissues from cancer patients, for instance, have their own distinct pattern of Thrombomodulin / CD141 expression as measured by anti-Thrombomodulin / CD141 antibody immunohistochemical staining. The average level of expression by tumor is summarized in the table below. The variability row represents patient to patient variability in IHC staining.| Sample Type | breast cancer | carcinoid | cervical cancer | colorectal cancer | endometrial cancer | glioma | head and neck cancer | liver cancer | lung cancer | lymphoma | melanoma | ovarian cancer | pancreatic cancer | prostate cancer | renal cancer | skin cancer | stomach cancer | testicular cancer | thyroid cancer | urothelial cancer |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Signal Intensity | - | - | ++ | - | - | - | + | - | - | - | - | - | - | - | - | ++ | - | - | - | - |
| THBD Variability | ++ | ++ | ++ | + | + | + | ++ | + | + | + | + | + | + | ++ | + | ++ | + | + | + | ++ |
Limitations and Warranty
enQuire Bio's Thrombomodulin / CD141 Anti-Human Monoclonal is available for Research Use Only. This antibody is guaranteed to work for a period of two years when properly stored.
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