Formalin-fixed, paraffin-embedded human Placenta stained with TIMP3 Rabbit Polyclonal Antibody.
Formalin-fixed, paraffin-embedded human Placenta stained with TIMP3 Rabbit Polyclonal Antibody.

Anti-TIMP-3 Antibody Clone

$ 488.00
Please Select Product Options Below To View The Catalog Number.

SKU: 7078-RBP1
Species: Human, Mouse, Rat, Horse, Cow, and Canine
Tested Applications: Flow Cytometry, Immunofluorescence, Immunohistochemistry (IHC)
Available Conjugates: Unconjugated
Isotype: Rabbit IgG
Mass Spec Validated?: Not MS Validated

Product NumberDescriptionPrice
7078-RBP1-P1 Size: 100 ug, Tag: Unconjugated
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In Stock.
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SKU: 7078-RBP1-P1
TIMP-3 General Information
Alternate Names
Metalloproteinase inhibitor 3, TIMP3, Tissue Inhibitor of Metalloproteinase 3
Molecular Weight
30kDa
Chromosomal Location
22q12.3
Curated Database and Bioinformatic Data
Gene SymbolTIMP3
Entrez Gene ID7078
Ensemble Gene IDENSG00000100234
RefSeq Protein Accession(s)NP_000353
RefSeq mRNA Accession(s)NM_000362,
RefSeq Genomic Accession(s)NG_029545, NC_000022, NC_018933, NG_009117
UniProt ID(s)P35625
UniGene ID(s)P35625
HGNC ID(s)11822
Cosmic ID(s)TIMP3
KEGG Gene ID(s)hsa:7078
PharmGKB ID(s)PA36528
General Description of TIMP-3.
TIMP3 (tissue inhibitor of metalloproteinases 3), along with family members TIMP1, TIMP2,, TIMP4, are inhibitors of the matrix metalloproteinases (MMPs), a group of peptidases involved in degradation of the extracellular matrix (ECM). An imbalance between MMPs, the associated TIMPs may play a significant role in the invasive phenotype of malignant tumors. TIMP s inhibit the proteolytic invasiveness of tumor cells, normal placental trophoblast cells. TIMP-3 may be involved in regulating trophoblastic invasion of the uterus as well as in regulating remodeling of the extracellular matrix during the folding of epithelia,, in the formation, branching, expansion of epithelial tubes.

Human, Mouse, Rat, Horse, Cow, and Canine Anti-TIMP-3 Antibody Product Attributes

Species: Human, Mouse, Rat, Horse, Cow, and Canine
Tested Applications: Flow Cytometry, Immunofluorescence, Immunohistochemistry (IHC).
Application Notes: Flow Cytometry (0.5-1ug of antibody/million cells in 0.1ml), Immunofluorescence (1-2ug of antibody/ml), Immunohistochemistry (IHC) (Formalin-fixed) (1-2ug of antibody/ml for 30 minutes at RT)
Clonality: Polyclonal
Anti-TIMP-3 Antibody Clone:
Clone Host and Isotype: Rabbit IgG
Anti-Human, Mouse, Rat, Horse, Cow, and Canine TIMP-3 Positive Control Sample: Placenta or breast carcinoma
Cellular Localization of Antibody Cytoplasmic
Buffer and Stabilizer: 10mM PBS with 0.05% BSA & 0.05% azide.
Antibody Concentration: 200ug/ml
Antibody Purification Method:Protein A/G Purified
Immunogen: ImmunogenImmunogen for TIMP3 Ab, is 100% homologous in human, cow, Canine, horse,, 94% homologous in mouse, rat.
Storage Conditions: Store at 2 to 8° C (refrigerate). Stable for 24 months when properly stored.

TIMP-3 Previously Observed Antibody Staining Patterns

Limitations and Warranty

enQuire Bio's TIMP-3 Anti-Human Polyclonal is available for Research Use Only. This antibody is guaranteed to work for a period of two years when properly stored.

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Anti-TIMP-3 Antibody Clone

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