Anti-von Willebrand Factor / Factor VIII Related-Ag Antibody Clone 3E2D10
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Tested Applications: Flow Cytometry, Immunofluorescence, Western Blot, Immunoprecipitation, Immunohistochemistry (IHC)
Available Conjugates: Unconjugated
Isotype: Mouse IgG1 kappa
Mass Spec Validated?: Not MS Validated
|7450-MSM1-P1||Size: 100 ug, Tag: Unconjugated|
Datasheets and Documentation
Certificate of Analysis and Tags (Coming Soon)SKU: 7450-MSM1-P1
|von Willebrand Factor / Factor VIII Related-Ag General Information|
|Von Willebrand Factor, vWF|
|Curated Database and Bioinformatic Data|
|Entrez Gene ID||7450|
|Ensemble Gene ID||ENSG00000110799|
|RefSeq Protein Accession(s)||NP_000543|
|RefSeq mRNA Accession(s)||NM_000552,|
|RefSeq Genomic Accession(s)||NC_000012, NC_018923, NG_009072|
|KEGG Gene ID(s)||hsa:7450|
|General Description of von Willebrand Factor / Factor VIII Related-Ag.|
|von Willebrand Factor (vWF) is a multimeric glycoprotein that is found in endothelial cells, plasma, platelets. It acts as a carrier protein for Factor VIII, promotes platelet adhesion, aggregation. vWF undergoes a variety of posttranslational modifications that influence the affinity, availability for Factor VIII, including cleavage of the propeptide, formation of N-terminal disulfide bonds. This antibody helps to establish the endothelial nature of some lesions of disputed histogenesis, e.g. Kaposis sarcoma, cardiac myxoma. It is widely used for differentiating vascular lesions from those of other tissue differentiation within a panel of other vascular markers although not all tumors of endothelial differentiation contain this antigen.|
Tested Applications: Flow Cytometry, Immunofluorescence, Western Blot, Immunoprecipitation, Immunohistochemistry (IHC).
Application Notes: Flow Cytometry (0.5-1ug of antibody/million cells in 0.1ml), Immunofluorescence (0.5-1ug of antibody/ml), Western Blot (0.5-1.0ug of antibody/ml), Immunoprecipitation (0.5-1 ug of antibody/500ug protein Lysate), Immunohistochemistry (IHC) (Formalin-fixed) (0.5-1.0ug of antibody/ml for 30 minutes at RT)
Anti-von Willebrand Factor / Factor VIII Related-Ag Antibody Clone: 3E2D10
Clone 3E2D10 Host and Isotype: Mouse IgG1 kappa
Anti-Human von Willebrand Factor / Factor VIII Related-Ag Positive Control Sample: HUVEC cells or Tonsil
Cellular Localization of Antibody Cytoplasmic
Buffer and Stabilizer: 10mM PBS with 0.05% BSA & 0.05% azide.
Antibody Concentration: 200ug/ml
Antibody Purification Method:Protein A/G Purified
Immunogen: Recombinant human vWF fragment spanning aa 845-949
Storage Conditions: Store at 2 to 8Â° C (refrigerate). Stable for 24 months when properly stored.
enQuire Bio's von Willebrand Factor / Factor VIII Related-Ag Anti-Human Monoclonal is available for Research Use Only. This antibody is guaranteed to work for a period of two years when properly stored.