Human Anti-CD1a / HTA1 (Mature Langerhans Cells Marker) Antibody Product Attributes
Tested Applications: IHC.
Anti-CD1a / HTA1 (Mature Langerhans Cells Marker) Antibody Clone: rC1A/711
Clone rC1A/711 Host and Isotype: Mouse IgG1, kappa
Anti-Human CD1a / HTA1 (Mature Langerhans Cells Marker) Positive Control Sample: MOLT-4 cells. Paracortex in a tonsil or a reactive lymph node.
Cellular Localization of Antibody rC1A/711 Staining: Cell Surface
Buffer and Stabilizer: 10mM PBS with 0.05% BSA & 0.05% azide. Also available without BSA & Azide.
Antibody Concentration: 200 ug/ml
Antibody Purification Method:Protein A/G purified from Bioreactor concentrate.
Immunogen: Recombinant full-length human CD1a protein
Storage Conditions: Store at 2 to 8 C (refrigerate). Stable for 24 months when properly stored.
CD1a / HTA1 (Mature Langerhans Cells Marker) Previously Observed Antibody Staining Patterns
Observed Antibody Staining Data By Tissue Type:Variations in CD1a / HTA1 antibody staining intensity in immunohistochemistry on tissue sections are present across different anatomical locations. An intense signal was observed in Langerhans in skin. More moderate antibody staining intensity was present in Langerhans in skin. Low, but measureable presence of CD1a / HTA1 could be seen infibroblasts in skin. We were unable to detect CD1a / HTA1 in other tissues. Disease states, inflammation, and other physiological changes can have a substantial impact on antibody staining patterns. These measurements were all taken in tissues deemed normal or from patients without known disease.
Observed Antibody Staining Data By Tissue Disease Status:Tissues from cancer patients, for instance, have their own distinct pattern of CD1a / HTA1 expression as measured by anti-CD1a / HTA1 antibody immunohistochemical staining. The average level of expression by tumor is summarized in the table below. The variability row represents patient to patient variability in IHC staining.
|Sample Type||breast cancer||carcinoid||cervical cancer||colorectal cancer||endometrial cancer||glioma||head and neck cancer||liver cancer||lung cancer||lymphoma||melanoma||ovarian cancer||pancreatic cancer||prostate cancer||renal cancer||skin cancer||stomach cancer||testicular cancer||thyroid cancer||urothelial cancer|
Limitations and Warranty
enQuire Bio's product, CD1a / HTA1 (Mature Langerhans Cells Marker) MonoSpecific Antibody, is available for Research Use Only (RUO-Only). This antibody is guaranteed to work for a period of two years when properly stored.
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