SDS-PAGE Analysis Purified CD21 / CR2 Mouse Monoclonal Antibody (CR2/1953).Confirmation of Integrity and Purity of Antibody.
SDS-PAGE Analysis Purified CD21 / CR2 Mouse Monoclonal Antibody (CR2/1953).Confirmation of Integrity and Purity of Antibody.Analysis of Protein Array containing more than 19,000 full-length human proteins using CD21 Mouse Monoclonal Antibody (CR2/1953) Z- and S- Score: The Z-score represents the strength of a signal that a monoclonal antibody (MAb) (in combination with a fluorescently-tagged anti-IgG secondary antibody) produces when binding to a particular protein on the HuProtTM array. Z-scores are described in units of standard deviations (SD’s) above the mean value of all signals generated on that array. If targets on HuProtTM are arranged in descending order of the Z-score, the S-score is the difference (also in units of SD’s) between the Z-score. S-score therefore represents the relative target specificity of a MAb to its intended target.  A MAb is considered to specific to its intended target, if the MAb has an S-score of at least 2.5. For example, if a MAb binds to protein X with a Z-score of 43 and to protein Y with a Z-score of 14, then the S-score for the binding of that MAb to protein X is equal to 29.Formalin-fixed, paraffin-embedded Human Tonsil stained with CD21 / CR2 Mouse Monoclonal Antibody (CR2/1953).

CD21 (Mature B-Cell & Follicular Dendritic Cell Marker) Ultraspecific Antibody

Tested against >20,000 Human Proteins

$ 199.00$ 429.00
Please Select Product Options Below To View The Catalog Number.

SKU: 1380-MSM3
Species: Human
Tested Applications: IHC
Available Conjugates: Unconjugated
Isotype: Mouse IgG1, kappa
Mass Spec Validated?: Not MS Validated

Product NumberDescriptionPrice
1380-MSM3-P0 Size: 20 ug, Tag: Unconjugated $ 228.00
1380-MSM3-P1 Size: 100 ug, Tag: Unconjugated $ 488.00
1380-MSM3-P1ABX Size: 100 ug, Tag: Unconjugated $ 488.00
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SKU: 1380-MSM3-P0
CD21 (Mature B-Cell & Follicular Dendritic Cell Marker) General Information
Alternate Names
CD21; Complement C3d receptor (C3DR); Complement Receptor type 2 (CR2); CVID7; EBV receptor; EBV-R; Epstein-Barr virus receptor; EVBR; SLEB9
Molecular Weight
140kDa
Chromosomal Location
Ships on blue ice.
Curated Database and Bioinformatic Data
Gene Symbol1380
Entrez Gene IDCR2
UniProt ID(s)P20023
UniGene ID(s)Hs445757
COSMIC ID Link(s)CR2
KEGG Gene ID(s)hsa:1380
General Description of CD21 (Mature B-Cell & Follicular Dendritic Cell Marker).
Recognizes a protein of 140kDa, which is identified as the complement receptor 2 (CR2) / CD21. This protein is expressed strongly on mature B cells, follicular dendritic cells and weakly on immature thymocytes and T lymphocytes. In B-cell ontogeny, CD21 appears after the pre-B-stage, is maintained during peripheral B-cell development and is lost upon terminal differentiation into plasma cells. CD21 expression is also gradually lost after stimulation of B cells in vitro. CD21 functions as receptor for C3d, C3dg and iC3b Complement components, for EBV and for IFNalpha. CD21 binds to CD23 and associates with CD19, CD81 and Leu13 to form a large signal-transduction complex involved in B cell activation.

Human Anti-CD21 (Mature B-Cell & Follicular Dendritic Cell Marker) Antibody Product Attributes

Species: Human
Tested Applications: IHC.
Clonality: Monoclonal
Anti-CD21 (Mature B-Cell & Follicular Dendritic Cell Marker) Antibody Clone: CR2/1953
Clone CR2/1953 Host and Isotype: Mouse IgG1, kappa
Anti-Human CD21 (Mature B-Cell & Follicular Dendritic Cell Marker) Positive Control Sample: WEHI-231 cells and Tonsil
Cellular Localization of Antibody CR2/1953 Staining: Cell Surface
Buffer and Stabilizer: 10mM PBS with 0.05% BSA & 0.05% azide. Also available without BSA & Azide.
Antibody Concentration: 200 ug/ml
Antibody Purification Method:Protein A/G purified from Bioreactor concentrate.
Immunogen: Recombinant fragment (apprx. aa 44-196) of human CR2 (CD21) protein (Please call for additional information.)
Storage Conditions: Store at 2 to 8 C (refrigerate). Stable for 24 months when properly stored.

CD21 (Mature B-Cell & Follicular Dendritic Cell Marker) Previously Observed Antibody Staining Patterns

Limitations and Warranty

enQuire Bio's product, CD21 (Mature B-Cell & Follicular Dendritic Cell Marker) MonoSpecific Antibody, is available for Research Use Only (RUO-Only). This antibody is guaranteed to work for a period of two years when properly stored.

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Tested against >20,000 Human Proteins

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CD21 (Mature B-Cell & Follicular Dendritic Cell Marker) Ultraspecific Antibody

Tested against >20,000 Human Proteins

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