Analysis of Protein Array containing >19,000 full-length human proteins using CD25 Mouse Monoclonal Antibody (IL2RA/2395)Z- and S- Score: The Z-score represents the strength of a signal that a monoclonal antibody (MAb) (in combination with a fluorescently-tagged anti-IgG secondary antibody) produces when binding to a particular protein on the HuProtTM array. Z-scores are described in units of standard deviations (SD’s) above the mean value of all signals generated on that array. If targets on HuProtTM are arranged in descending order of the Z-score, the S-score is the difference (also in units of SD’s) between the Z-score. S-score therefore represents the relative target specificity of a MAb to its intended target.  A MAb is considered to specific to its intended target, if the MAb has an S-score of at least 2.5. For example, if a MAb binds to protein X with a Z-score of 43 and to protein Y with a Z-score of 14, then the S-score for the binding of that MAb to protein X is equal to 29.
Analysis of Protein Array containing >19,000 full-length human proteins using CD25 Mouse Monoclonal Antibody (IL2RA/2395)Z- and S- Score: The Z-score represents the strength of a signal that a monoclonal antibody (MAb) (in combination with a fluorescently-tagged anti-IgG secondary antibody) produces when binding to a particular protein on the HuProtTM array. Z-scores are described in units of standard deviations (SD’s) above the mean value of all signals generated on that array. If targets on HuProtTM are arranged in descending order of the Z-score, the S-score is the difference (also in units of SD’s) between the Z-score. S-score therefore represents the relative target specificity of a MAb to its intended target.  A MAb is considered to specific to its intended target, if the MAb has an S-score of at least 2.5. For example, if a MAb binds to protein X with a Z-score of 43 and to protein Y with a Z-score of 14, then the S-score for the binding of that MAb to protein X is equal to 29.SDS-PAGE Analysis Purified CD25Mouse Monoclonal Antibody (IL2RA/2395).Confirmation of Integrity and Purity of Antibody

CD25/ IL2RA (Activated Lymphocyte Marker) Ultraspecific Antibody

Tested against >20,000 Human Proteins

$ 228.00$ 488.00
Please Select Product Options Below To View The Catalog Number.

SKU: 3559-MSM5
Species: Human
Tested Applications: IHC
Available Conjugates: Unconjugated
Isotype: Mouse IgG2b
Mass Spec Validated?: Not MS Validated

Product NumberDescriptionPrice
3559-MSM5-P0 Size: 20 ug, Tag: Unconjugated $ 199.00
3559-MSM5-P1 Size: 100 ug, Tag: Unconjugated $ 429.00
3559-MSM5-P1ABX Size: 100 ug, Tag: Unconjugated $ 429.00
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SKU: 3559-MSM5-P0
CD25/ IL2RA (Activated Lymphocyte Marker) General Information
Alternate Names
IL2 Receptor alpha; IL2R alpha chain; IL2R; IL2R subunit alpha IL2RA; Interleukin-2 receptor subunit alpha; Ly43; p55; p55 chain; T Cell Growth Factor Receptor; TAC antigen; TCGFR
Molecular Weight
55kDa
Chromosomal Location
Ships on blue ice.
Curated Database and Bioinformatic Data
Gene Symbol3559
Entrez Gene IDIL2RA
UniProt ID(s)P01589
UniGene ID(s)Hs231367
COSMIC ID Link(s)IL2RA
KEGG Gene ID(s)hsa:3559
General Description of CD25/ IL2RA (Activated Lymphocyte Marker).
Recognizes a protein of 55kDa, identified as CD25.It is expressed on activated T- and B-cells and activated monocytes/macrophages.With respect to lymphomas, CD25 is present on malignant cells of Hodgkin s disease, HTLV-1+ adult T-cell leukemia, cutaneous T-cell lymphoma, and hair cell leukemia. Increased levels of soluble CD25 are observed in the leukemias/lymphomas and inflammatory/ autoimmune diseases. CD25 molecule alone appears to function as a low affinity receptor and associates with CD122 (IL-2R  chain, p75) and CD132 (common chain) to form the high affinity IL-2 receptor complex.CD25 antibodies detect three epitope regions, A, B and C. This MAb recognizes the epitope B, which is located at residue 3-104 of CD25 and doe not block IL-2 binding to CD25.

Human Anti-CD25/ IL2RA (Activated Lymphocyte Marker) Antibody Product Attributes

Species: Human
Tested Applications: IHC.
Clonality: Monoclonal
Anti-CD25/ IL2RA (Activated Lymphocyte Marker) Antibody Clone: IL2RA/2395
Clone IL2RA/2395 Host and Isotype: Mouse IgG2b
Anti-Human CD25/ IL2RA (Activated Lymphocyte Marker) Positive Control Sample: PHA-stimulated human lymphocytes. Human lymph nodeor tonsil
Cellular Localization of Antibody IL2RA/2395 Staining: Cell Surface and Cytoplasmic
Buffer and Stabilizer: 10mM PBS with 0.05% BSA & 0.05% azide. Also available without BSA & Azide.
Antibody Concentration: 200 ug/ml
Antibody Purification Method:Protein A/G purified from Bioreactor concentrate.
Immunogen: Recombinantfragment of human IL2RA protein (apprx. aa 42-183) (Please call for additional information.)
Storage Conditions: Store at 2 to 8 C (refrigerate). Stable for 24 months when properly stored.

CD25/ IL2RA (Activated Lymphocyte Marker) Previously Observed Antibody Staining Patterns

Limitations and Warranty

enQuire Bio's product, CD25/ IL2RA (Activated Lymphocyte Marker) MonoSpecific Antibody, is available for Research Use Only (RUO-Only). This antibody is guaranteed to work for a period of two years when properly stored.

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Tested against >20,000 Human Proteins

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CD25/ IL2RA (Activated Lymphocyte Marker) Ultraspecific Antibody

Tested against >20,000 Human Proteins

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