SDS-PAGE Analysis Purified Cytokeratin 10 Rabbit Recombinant MAb (KRT10/1990R).Confirmation of Purity and Integrity of Antibody.
SDS-PAGE Analysis Purified Cytokeratin 10 Rabbit Recombinant MAb (KRT10/1990R).Confirmation of Purity and Integrity of Antibody.

Cytokeratin 10 (KRT10) (Suprabasal Epithelial Marker) Ultraspecific Antibody

Tested against >20,000 Human Proteins

$ 199.00$ 429.00
Please Select Product Options Below To View The Catalog Number.

SKU: 3858-RBM10
Species: Human and Mouse
Tested Applications: Flow, IF, IHC
Available Conjugates: Unconjugated
Isotype: Rabbit IgG
Mass Spec Validated?: Not MS Validated

Product NumberDescriptionPrice
3858-RBM10-P0 Size: 20 ug, Tag: Unconjugated $ 199.00
3858-RBM10-P1 Size: 100 ug, Tag: Unconjugated $ 429.00
3858-RBM10-P1ABX Size: 100 ug, Tag: Unconjugated $ 429.00
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In Stock.
Flat Rate Shipping Anywhere in the US: $45
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SKU: 3858-RBM10-P0
Cytokeratin 10 (KRT10) (Suprabasal Epithelial Marker) General Information
Alternate Names
BCIE, BIE, EHK, Keratin Type I Cytoskeletal 10, KRT10
Molecular Weight
56.5kDa
Chromosomal Location
Ships on blue ice.
Curated Database and Bioinformatic Data
Gene Symbol3858
Entrez Gene IDKRT10
UniProt ID(s)P13645
UniGene ID(s)Hs99936
COSMIC ID Link(s)KRT10
KEGG Gene ID(s)hsa:3858
General Description of Cytokeratin 10 (KRT10) (Suprabasal Epithelial Marker).
This MAb recognizes a protein of 56.5kDa, identified as cytokeratin 10 (CK10). CK10 is expressed in all suprabasal layers of the epidermis. In the epidermis, expression of CK10 strictly parallels the extent of differentiation; it is absent in the basal layer, appears in the first suprabasal layers and increases in concentration towards the granular layer. However, CK10 is rarely detected in early stages of vulvar squamous carcinomas (tumors less than 2 cm, clinical stage I) regardless of the tumor grade. In larger and more advanced tumors (greater than 2 cm, clinical stages II and III), CK10 is detected very frequently. Expression of CK10 is related to maturation of malignant keratinocytes, being preferentially detected in more-differentiated parts.

Human and Mouse Anti-Cytokeratin 10 (KRT10) (Suprabasal Epithelial Marker) Antibody Product Attributes

Species: Human and Mouse
Tested Applications: Flow, IF, IHC.
Clonality: Monoclonal
Anti-Cytokeratin 10 (KRT10) (Suprabasal Epithelial Marker) Antibody Clone: KRT10/1990R
Clone KRT10/1990R Host and Isotype: Rabbit IgG
Anti-Human and Mouse Cytokeratin 10 (KRT10) (Suprabasal Epithelial Marker) Positive Control Sample: A431, HeLa, MCF7 cells. Esophagus or tonsil.
Cellular Localization of Antibody KRT10/1990R Staining: Cytoplasmic
Buffer and Stabilizer: 10mM PBS with 0.05% BSA & 0.05% azide. Also available without BSA & Azide.
Antibody Concentration: 200 ug/ml
Antibody Purification Method:Protein A/G purified from Bioreactor concentrate.
Immunogen: Skin extract of a human Psoriasis patient
Storage Conditions: Store at 2 to 8 C (refrigerate). Stable for 24 months when properly stored.

Cytokeratin 10 (KRT10) (Suprabasal Epithelial Marker) Previously Observed Antibody Staining Patterns

Observed Antibody Staining Data By Tissue Type:

Variations in Cytokeratin 10 antibody staining intensity in immunohistochemistry on tissue sections are present across different anatomical locations. An intense signal was observed in epidermal cells in the skin and keratinocytes in skin. More moderate antibody staining intensity was present in epidermal cells in the skin and keratinocytes in skin. Low, but measureable presence of Cytokeratin 10 could be seen in. We were unable to detect Cytokeratin 10 in other tissues. Disease states, inflammation, and other physiological changes can have a substantial impact on antibody staining patterns. These measurements were all taken in tissues deemed normal or from patients without known disease.

Limitations and Warranty

enQuire Bio's product, Cytokeratin 10 (KRT10) (Suprabasal Epithelial Marker) MonoSpecific Antibody, is available for Research Use Only (RUO-Only). This antibody is guaranteed to work for a period of two years when properly stored.

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Cytokeratin 10 (KRT10) (Suprabasal Epithelial Marker) Ultraspecific Antibody

Tested against >20,000 Human Proteins

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